Evidence supporting the use of: Vitamin E
For the body system: Arteries

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin E is an antioxidant that has been studied for its potential role in cardiovascular health, including the support of arterial function. The rationale stems from its ability to reduce oxidative stress and inhibit the oxidation of low-density lipoprotein (LDL) cholesterol, which is a key step in the development of atherosclerosis—a condition characterized by the hardening and narrowing of the arteries. Early observational studies suggested that higher vitamin E intake might be associated with a reduced risk of coronary artery disease. However, large randomized controlled trials, such as the HOPE and the Women's Health Study, have not demonstrated significant cardiovascular benefits from vitamin E supplementation in the general population. Additionally, meta-analyses have failed to show a reduction in cardiovascular events with vitamin E supplements, and some have suggested a possible increase in all-cause mortality at high doses. Despite this, vitamin E remains of scientific interest for its biological plausibility and antioxidant properties. Currently, major health organizations do not recommend vitamin E supplementation solely for the prevention or treatment of arterial or cardiovascular disease in those without specific deficiencies. In summary, while vitamin E has a scientifically plausible mechanism for arterial support, clinical evidence for its benefit in this context is limited and inconsistent.

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black currant
black garlic
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fiber blend (proprietary)
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