Evidence supporting the use of: Vitex (unspecified)
For the health condition: Amenorrhea

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Vitex agnus-castus, commonly known as chaste tree or chasteberry, has a long history of traditional use in treating menstrual disorders, including amenorrhea (absence of menstruation). Its therapeutic use dates back to Ancient Greece and Rome, where it was believed to influence female reproductive health. In traditional European herbal medicine, Vitex has been employed to address various menstrual irregularities, including both absent and irregular periods.

The proposed mechanism of action is thought to involve modulation of the pituitary gland, particularly influencing prolactin secretion, which can affect the menstrual cycle. Some small clinical studies and observational reports have suggested that Vitex may help regulate the menstrual cycle, especially in cases related to mild hyperprolactinemia or luteal phase defects. However, high-quality randomized controlled trials specifically examining Vitex for amenorrhea are lacking, and most of the evidence comes from broader studies on menstrual disorders or from anecdotal reports.

Overall, the use of Vitex for amenorrhea is primarily justified by traditional and historical usage, with modest preliminary scientific support but insufficient rigorous clinical evidence. Therefore, it is commonly recommended by herbalists and alternative medicine practitioners, but not widely endorsed by mainstream medical guidelines for this specific condition.

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