Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Coleus forskohlii root has a history of traditional use in Ayurvedic medicine, notably for respiratory conditions such as asthma and allergies. The root contains the active compound forskolin, which is known to increase cyclic AMP (cAMP) levels in cells. Historically, increased cAMP has been associated with bronchodilation and decreased histamine release from mast cells, suggesting a potential mechanism for reducing allergy symptoms. Traditional practitioners have used forskohlii preparations to support respiratory health, including alleviating symptoms associated with allergic reactions like nasal congestion, wheezing, and shortness of breath.

On the scientific front, some small clinical studies and animal models have investigated forskolin’s effects on asthma and allergy symptoms. These studies suggest a possible benefit, such as reduced airway reactivity and decreased histamine release, but data remain limited and inconsistent. Comprehensive, high-quality clinical trials are lacking, so the scientific evidence is not robust enough to warrant a higher rating. Thus, while traditional use is well-documented, modern scientific validation is modest and inconclusive, supporting a rating of 2 for evidence.

In summary, use of Coleus forskohlii root for treating or supporting respiratory allergies is primarily based on traditional medicine with some preliminary scientific interest, but not yet strong scientific validation.

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