Evidence supporting the use of: Vitamin E (mixied tocopherols and tocotrienols)
For the health condition: Aging (prevention)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin E, which includes both tocopherols and tocotrienols, is commonly marketed and studied for its potential anti-aging effects due to its antioxidant properties. The rationale is that oxidative stress contributes to cellular aging and that Vitamin E, as a lipid-soluble antioxidant, may help neutralize free radicals, thereby slowing the aging process. Preclinical studies (in vitro and animal models) show that Vitamin E can reduce oxidative damage to cells and tissues. Some small human studies have suggested possible benefits for skin aging (e.g., reducing wrinkle formation and improving skin moisture), especially when used topically or in combination with other antioxidants.

However, large-scale clinical trials evaluating oral Vitamin E supplementation for general aging, longevity, or prevention of age-related diseases in humans have yielded mixed or disappointing results. Meta-analyses and systematic reviews generally conclude that there is insufficient evidence that Vitamin E supplementation significantly slows aging or extends lifespan in the general population. Concerns have also been raised about the safety of high-dose Vitamin E supplementation, which may increase the risk of certain adverse events (e.g., hemorrhagic stroke).

In summary, while there is a plausible scientific basis and some supportive preclinical evidence, robust clinical evidence supporting the use of Vitamin E for aging prevention in humans is limited. Therefore, the level of evidence is rated as 2 (weak), mainly based on mechanistic and preclinical data rather than strong human clinical trials.

More about Vitamin E (mixied tocopherols and tocotrienols)
More about Aging (prevention)

Other ingredients used for Aging (prevention)

7-hydroxymatairesinol (HMR)
7-Keto-DHEA
acai berry
acetyl l-carnitine
akkermansia muciniphila
algal oil
alpha-carotene
alpha-glycosyl isoquercitrin
alpha-ketoglutarate (AKG)
alpha-linolenic acid (ALA)
amino acids
anthocyanins
apple
apricot
ascorbyl palmitate
ashwagandha
astaxanthin
astragalus
beta-carotene
brussel sprouts
carrot
catalase
cauliflower
coenzyme Q10 (CoQ10)
collagen
cryptoxanthin
turmeric
curcumin
DHEA (dehydroepiandrosterone)
epigallocatechin gallate (EGCG)
fisetin
flaxseed
ginkgo biloba
green tea
greens blend (proprietary)
l-carnosine
lutein
magnesium
matcha
melatonin
mixed carotenoids
nicotinamide riboside
omega-3 fatty acids
polypeptide complex (proprietary)
protein
quercetin
resveratrol
rhodiola
sardines
selenium
silicon
soybean
trans-pterostilbene
almond fruit
Urolithin A
vegetable blend (proprietary)
vitamin A
vitamin C
vitamin E
watermelon
zinc
β-nicotinamide mononucleotide (NMN)
cistanche
dodder
royal jelly
polyphenols
anemarrhena asphodeloides
yerba mate
goji berry
algae
AMP-activated protein kinase (AMPK)
soy isoflavones
ashitaba
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
8-Prenylnaringenin
Antler
Apigenin
Aronia melanocarpa
Antrodia camphorata
Anserine
Avocado
Alpha Hydroxy Acids
Allantoin
Alpha-Lipoic Acid
Astragaloside
anthocyanidins
Ampelopsin
Algal protein
anthocyanosides
Argan nut oil
Abalone
Brassica
Bioflavonoids
Bird's nest
Carnosine
Curcuminoid
Cruciferous
Cycloastragenol
Chinese Ligustrum berry
Carotene (unspecified)
Dunaliella salina
Dismutase
DHEA
Dunaliella
Epidermal Growth Factor
epicatechin
Ellagic Acid
Ergothioneine
Flavonoids
Fo-Ti
Fucoxanthin
fibroblast growth factor
Ginsenosides
Gac
Gerovital H3
Glabridin

Products containing Vitamin E (mixied tocopherols and tocotrienols)

We currently have no products on Caring Sunshine that contain this ingredient.