Evidence supporting the use of: Omega-3 fatty acids
For the health condition: Aging (prevention)
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Omega-3 fatty acids, particularly EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid), have a moderate level of scientific evidence supporting their role in the prevention or slowing of aging-related decline, primarily through cardiovascular, cognitive, and anti-inflammatory effects. Multiple epidemiological studies have associated higher intake of omega-3 fatty acids with reduced risk of cardiovascular disease, a major aging concern. Randomized controlled trials (RCTs) and meta-analyses suggest modest benefits for heart health, including reduced triglycerides and lowered risk of cardiac events, although the effect on overall mortality in the elderly is still debated.
In terms of cognitive aging, some studies indicate that omega-3 supplementation may slow cognitive decline in older adults, particularly those with mild cognitive impairment, but results are mixed, and benefits are less pronounced in those with established dementia. The anti-inflammatory properties of omega-3s are also theorized to contribute to healthier aging by reducing systemic inflammation, a process linked to age-related diseases. However, the evidence here is considered moderate, not definitive.
Overall, omega-3 fatty acids are not a cure-all for aging, but there is a reasonable scientific rationale and moderate clinical evidence for their use in supporting healthy aging, especially in the context of heart and brain health. Their use is supported by dietary guidelines and recommended for most adults, particularly those at risk for cardiovascular disease.
More about omega-3 fatty acids
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Other ingredients used for Aging (prevention)
7-hydroxymatairesinol (HMR)7-Keto-DHEA
Acai berry
Acetyl L-carnitine
Akkermansia muciniphila
algal oil
Alpha-carotene
alpha-glycosyl isoquercitrin
alpha-ketoglutarate (AKG)
alpha-linolenic acid (ALA)
amino acids
anthocyanins
apple
apricot
ascorbyl palmitate
ashwagandha
astaxanthin
astragalus
beta-carotene
Brussel sprouts
carrot
catalase
cauliflower
coenzyme Q10 (CoQ10)
collagen
cryptoxanthin
turmeric
curcumin
DHEA (dehydroepiandrosterone)
epigallocatechin gallate (EGCG)
fisetin
flaxseed
ginkgo biloba
green tea
greens blend (proprietary)
L-carnosine
lutein
magnesium
Matcha
Melatonin
mixed carotenoids
nicotinamide riboside
omega-3 fatty acids
polypeptide complex (proprietary)
protein
quercetin
resveratrol
Rhodiola
sardines
selenium
silicon
soybean
Trans-pterostilbene
Almond fruit
Urolithin A
vegetable blend (proprietary)
vitamin A
vitamin C
vitamin E
Watermelon
Zinc
β-nicotinamide mononucleotide (NMN)
cistanche
dodder
royal jelly
polyphenols
anemarrhena asphodeloides
Yerba mate
goji berry
Algae
AMP-activated protein kinase (AMPK)
soy isoflavones
ashitaba
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
8-Prenylnaringenin
antler
apigenin
Aronia melanocarpa
Antrodia camphorata
anserine
avocado
Alpha hydroxy acids
Allantoin
alpha-lipoic acid
astragaloside
anthocyanidins
ampelopsin
Algal protein
anthocyanosides
argan nut oil
Abalone
Brassica
bioflavonoids
bird\'s nest
Carnosine
Curcuminoid
cruciferous
cycloastragenol
Chinese Ligustrum berry
carotene (unspecified)
Dunaliella salina
dismutase
DHEA
Dunaliella
Epidermal Growth Factor
epicatechin
ellagic acid
ergothioneine
flavonoids
fo-ti
fucoxanthin
fibroblast growth factor
Ginsenosides
Gac
Growth factors
Gerovital H3
Glabridin
hydroxymethylbutyrate
Haematococcus pluvialis
HMB hydroxymethylbutyrate
hazelnut
icariin
Lycium
Oligomeric proanthocyanidins
oolong tea
pyrroloquinoline quinone
Phytofluene
Phytoene
Peptides
Squalene
Salidroside
Shilajit
Triterpenes
Tremella
Xanthophyll
Other health conditions supported by omega-3 fatty acids
AcneAcquired Immune Deficiency Syndrome
Addictions (drugs)
Addictions (general remedies for)
Addictions (tobacco smoking or chewing)
Aging (prevention)
Alcoholism
Allergies (food)
Allergies (respiratory)
Alzheimer's Disease
Angina
Anorexia
Anxiety
Anxiety Disorders
Apathy
Arrhythmia
Arteriosclerosis
Anger (excessive)
Arthritis
Asthma
Athletic and Exercise Aids
Attention Deficit Disorder
Autism
Autoimmune Disorders
Backache
Bipolar Mood Disorder
Birth Defects (prevention)
Blood Clots (prevention of)
Bloodshot Eyes
Body Building
Broken Bones
Bulimia
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Canker Sores
Cardiovascular Disease
Cartilage Damage
Cholesterol (high)
Cholesterol (low)
Chronic Obstructive Pulmonary Disorder
Circulation (poor)
Circulation (to the brain)
Concentration (poor)
Concussions
Confusion
Congestive Heart Failure
Dementia
Depression
Diabetes
Dysmenorrhea
Eczema
Emotional Sensitivity
Endometriosis
Epilepsy
Exercise
Eye Problems
Eyes (red or itching)
Eyesight (poor)
Fat Metabolism (poor)
Fatigue
Fatty Liver Disease
Fibrosis
Free Radical Damage
Glaucoma
Gout
Hair (loss or thinning)
Hair Care (general)
Hashimoto's Disease
Hearing Loss
Heart (weakness)
Heart Fibrillation or Palpitations
Hepatitis
Hypertension
Infertility
Inflammation
Inflammatory Bowel Disorders
Irritability
Lou Gehrig's Disease
Lupus
Macular Degeneration
Memory and Brain Function
Menopause
Metabolic Syndrome
Migraine
Muscular Dystrophy
Nerve Damage
Neuralgia and Neuritis
Numbness
Osteoporosis
Parkinson's Disease
Peripheral Neuropathy
Pets (supplements for)
PMS Type D
PMS Type P
PMS Type S
Polyps
Post Partum Depression
Post Partum Weakness
Pregnancy (herbs and supplements for)
Psoriasis
Raynaud's Disease
Rheumatoid Arthritis
Rosacea
Schizophrenia
Seasonal Affective Disorder
Seborrhea
Seizures
Senility
Sickle Cell Anemia
Skin (dry and/or flaky)
Skin Care (general)
Spinal Disks
Strokes
Surgery (healing from)
Surgery (preparation for)
Thinking (cloudy)
Thrombosis
Triglycerides (high)
Triglycerides (low)
Vaginal Dryness