Evidence supporting the use of: Adrenals
For the body system: Adrenal Cortex
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Adrenal glandular supplements, often labeled as "Adrenals," are derived from the adrenal glands of animals (commonly bovine sources). These supplements have been used in alternative medicine to support the adrenal cortex, which is responsible for producing vital hormones such as cortisol, aldosterone, and certain androgens. The scientific rationale for their use is based on the concept of "like supports like," suggesting that consuming adrenal tissue may provide nutrients or factors that support adrenal function in humans.
However, the scientific evidence supporting the efficacy of adrenal glandular supplements is limited. Most available data are anecdotal or based on historical use in naturopathic and integrative medicine. There is a lack of robust, peer-reviewed clinical trials demonstrating measurable benefits for adrenal health, adrenal insufficiency, or related conditions such as fatigue or Addison's disease. Theoretical concerns also exist regarding the safety and standardization of these products, as they may contain variable amounts of active hormones or other bioactive substances.
In summary, while adrenal glandulars are used in some alternative medicine circles to support adrenal cortex function, scientific validation is weak. Most evidence is either anecdotal or derived from outdated practices, and mainstream medical organizations do not recommend their use for adrenal support. The evidence rating is therefore 2 out of 5, reflecting some scientific rationale but insufficient clinical validation.
Other ingredients that support Adrenal Cortex
ashwagandhaastragalus
bovine
bovine kidney
bovine liver
bupleurum falcatum
caterpillar mushroom
DHEA (dehydroepiandrosterone)
eleuthero
ginseng
guayusa
licorice root
maca
pantothenic acid (vitamin B5)
phellodendron amurense
phosphatidylserine
rehmannia glutinosa
reishi mushroom
relora® (proprietary)
rhodiola
vitamin B
whole adrenal glandular
suma
lingzhi
sodium salt
dioscorea
ganoderma
anemarrhena asphodeloides
herbal blend (proprietary)
sea salt
Aralia
Animal Tissue
Black spruce
Black galingale
Bulbine natalensis
Barbasco
Clary sage
Cortisol
Coca
Chinese Thoroughwax
DHEA
Eurycoma Longifolia
Ginsenosides
Glycyrrhetinic Acid
Glycyrrhizin
salt
Other body systems supported by Adrenals
Adrenal CortexCortisol
Glandular System
Sympathetic Nervous System