Evidence supporting the use of: Lophatherum
For the health condition: Adenitis

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Lophatherum, specifically the leaves of Lophatherum gracile (commonly called "Danzhuye" in traditional Chinese medicine), has been traditionally used in herbal medicine systems—particularly in East Asia—for its purported heat-clearing and detoxifying properties. In the context of adenitis (inflammation of the lymph glands), Lophatherum is not a primary or direct remedy but is often included in formulas aimed at treating febrile diseases, sore throat, mouth ulcers, and other conditions that may overlap symptomatically with adenitis. The rationale for its use is based on the traditional classification of Lophatherum as a "cooling" and "heat-relieving" herb that can address internal "heat" and facilitate urination, thereby helping to reduce swelling and inflammation indirectly. Scientific studies on Lophatherum's efficacy for adenitis specifically are lacking. Some pharmacological research has demonstrated anti-inflammatory, antibacterial, and diuretic effects in vitro and in animal models, but these studies are not directly tied to adenitis or lymphatic inflammation. Therefore, the use of Lophatherum for adenitis is primarily justified by traditional practice rather than robust scientific evidence. It is commonly used as a supportive rather than a central herb in formulas for inflammatory conditions in Chinese herbal medicine, with its application for adenitis being inferred from its general anti-inflammatory and heat-clearing properties rather than direct clinical trials.

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