Evidence supporting the use of: N-Acetyl Cysteine
For the health condition: Addictions (coffee, caffeine)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

N-Acetyl Cysteine (NAC) has garnered scientific interest for its potential role in supporting treatment of various addictions, including those related to substances like nicotine, cannabis, and cocaine. The rationale for its use is based on its ability to modulate glutamatergic and dopaminergic neurotransmission in the brain, pathways known to be involved in addiction and reward. NAC is thought to help restore extracellular glutamate concentrations in the nucleus accumbens, a region implicated in addictive behaviors, thereby reducing cravings and compulsive use.

For caffeine or coffee addiction specifically, there is very limited direct research. Most of the scientific literature and clinical trials focus on other substances of abuse. However, the mechanisms by which NAC acts are not substance-specific, suggesting a theoretical basis for its use in caffeine addiction. The evidence for effectiveness in caffeine addiction is therefore extrapolated from studies on other addictions, and remains weak.

In summary, while there is preliminary scientific validation for NAC in the treatment of some types of addiction, the evidence specific to coffee or caffeine addiction is sparse and indirect. The overall quality of evidence for this specific use is low (rated 2/5), and more research is needed to confirm any benefit for caffeine-related disorders.

More about N-Acetyl Cysteine
More about Addictions (coffee, caffeine)

Other ingredients used for Addictions (coffee, caffeine)

chicory
ginseng
green tea
kudzu
l-theanine
passionflower
water
yerba mate

Products containing N-Acetyl Cysteine

We currently have no products on Caring Sunshine that contain this ingredient.