Evidence supporting the use of: Phosphatidylserine complex
For the body system: Acetylcholine

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Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Phosphatidylserine (PS) is a phospholipid component found in high concentrations in brain cell membranes and has been studied for its roles in cognitive function. While PS itself is not a direct precursor to acetylcholine (ACh), it is believed to support the cholinergic system by maintaining neuronal membrane fluidity and facilitating neurotransmitter release, including acetylcholine. Several clinical studies, particularly those involving elderly subjects with memory complaints or cognitive decline, have shown modest benefits for memory and cognitive performance following phosphatidylserine supplementation. Some research indicates that PS may help sustain acetylcholine levels or receptor function under stress or aging conditions, which could theoretically support the "acetylcholine body system"—that is, the networks and functions reliant on this neurotransmitter. However, the bulk of evidence is modest and not all studies demonstrate significant effects. Most research uses PS derived from soy or bovine sources, and safety is well established. Overall, the scientific evidence rates as moderate (3/5): there is documented support for cognitive health, and PS may indirectly benefit acetylcholine-related functions, but it is not a primary or direct acetylcholine precursor like choline itself. There is no significant "traditional" use of PS for this purpose; its use in this context is based on modern biochemical and clinical research.

More about Phosphatidylserine complex
More about Acetylcholine

Other body systems supported by Phosphatidylserine complex

Acetylcholine
Brain
Cortisol
Hypothalamus
Specific Neurotransmitters
Sympathetic Nervous System

Products containing Phosphatidylserine complex

We currently have no products on Caring Sunshine that contain this ingredient.