Evidence supporting the use of: Chinese Club Moss
For the body system: Acetylcholine

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Chinese Club Moss (Huperzia serrata) is often used in dietary supplements intended to support the acetylcholine system, primarily due to its active compound, huperzine A. Huperzine A is a natural alkaloid that functions as an acetylcholinesterase inhibitor, meaning it slows the breakdown of acetylcholine, a neurotransmitter vital for memory and learning. Several small-scale human studies and animal research have investigated huperzine A’s effects, especially relating to cognitive function and Alzheimer’s disease. Some clinical trials, mainly conducted in China, have shown modest cognitive benefits in people with Alzheimer’s and other cognitive impairments when using huperzine A compared to placebo. These findings suggest a mechanism that could support acetylcholine activity in the brain.

However, the overall quality of evidence remains limited. Many studies have methodological weaknesses, small sample sizes, or lack rigorous controls. Systematic reviews and meta-analyses conclude that while there is potential, the evidence is not robust enough to definitively recommend huperzine A as a treatment for cognitive decline or for general acetylcholine support. The use of Chinese Club Moss for this purpose is therefore justified by some scientific research, but the strength of the evidence is modest (rated 2 out of 5). More well-designed, large-scale clinical trials are needed for definitive conclusions.

More about Chinese Club Moss
More about Acetylcholine

Other body systems supported by Chinese Club Moss

Acetylcholine
Brain
Nerves
Specific Neurotransmitters

Products containing Chinese Club Moss

We currently have no products on Caring Sunshine that contain this ingredient.