Other names for Oxypregnane glycoside

oxypregnane steroidal glycoside

Synopsis of Oxypregnane glycoside

History

Oxypregnane glycoside is a naturally occurring compound predominantly found in several medicinal plants, particularly within the Asclepiadaceae family. Historically, these compounds have played a significant role in traditional herbal medicine, especially in regions of Asia and Africa. Plants such as Cynanchum auriculatum, Caralluma fimbriata, and Gymnema sylvestre are rich sources of oxypregnane glycosides and have been used for centuries to address a variety of health conditions.

Traditional remedies incorporating oxypregnane glycoside-rich plants have been employed to help regulate blood sugar levels, support weight management, and promote digestive health. For instance, Caralluma fimbriata has been widely used in Indian folk medicine as an appetite suppressant and to improve stamina during long hunts or periods of food scarcity. Similarly, Gymnema sylvestre is renowned in Ayurvedic medicine for its role in supporting healthy glucose metabolism, earning the moniker "sugar destroyer."

Oxypregnane glycosides are often used in combination with other herbal ingredients to enhance their therapeutic effects. In traditional formulas, they are blended with botanicals such as fenugreek, bitter melon, and holy basil to support metabolic health and general wellness. These herbal combinations are thought to work synergistically, maximizing benefits while minimizing side effects. Modern research has begun to validate many of these traditional uses, confirming the positive contributions of oxypregnane glycosides in supporting healthy metabolism, appetite control, and overall well-being. Their inclusion in nutritional products underscores their enduring value as potent, natural agents for health promotion.

Traditional and scientific validation

Oxypregnane glycosides are naturally occurring compounds predominantly found in certain plant species, especially within the Asclepiadaceae family, such as Hoodia gordonii and Caralluma fimbriata. Traditionally, plants containing oxypregnane glycosides have been utilized in folk medicine for appetite suppression and weight management, particularly in regions of Africa and India. This ethnobotanical use has spurred scientific interest into their mechanisms and benefits.

Scientific inquiry has revealed that oxypregnane glycosides may influence appetite-regulating pathways. For example, studies on Hoodia gordonii have suggested that these glycosides could impact the hypothalamus, the brain’s appetite control center, potentially leading to reduced food intake. Similarly, extracts from Caralluma fimbriata standardized for oxypregnane glycoside content have been the subject of several clinical trials. A few double-blind, placebo-controlled studies have demonstrated modest reductions in appetite and waist circumference among overweight individuals consuming these extracts over several weeks.

Despite these promising results, the overall body of evidence remains limited. Larger, long-term clinical trials are still needed to fully validate the efficacy and safety of oxypregnane glycosides for nutritional and therapeutic purposes. Nevertheless, early findings suggest that oxypregnane glycosides could contribute positively as supportive agents in weight management and appetite modulation. Their traditional use alongside emerging scientific data continues to encourage further research into their potential health benefits.

Oxypregnane glycoside is used for these health conditions

Fatigue (Traditional)
Inflammation (Traditional)
Wounds and Sores (Traditional)

This ingredient is used to support these body systems

None

Products containing Oxypregnane glycoside

We currently have no products on Caring Sunshine that contain this ingredient.