Myasthenia Gravis

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Other names for Myasthenia Gravis

MG
Autoimmune neuromuscular disorder
Chronic muscle fatigue syndrome
Neuromuscular junction disease

Synopsis of Myasthenia Gravis

Myasthenia gravis (MG) is a chronic autoimmune neuromuscular disorder characterized by weakness and rapid fatigue of voluntary muscles. It occurs when the immune system produces antibodies that block or destroy acetylcholine receptors at the neuromuscular junction, preventing effective communication between nerves and muscles. This impairs the muscles' ability to contract, particularly during sustained activity.

The condition can affect people of any age, but it’s more common in women under 40 and men over 60. While there is no cure, early diagnosis and treatment can greatly improve quality of life.

Common symptoms:

  • Muscle weakness that worsens with activity and improves with rest

  • Drooping eyelids (ptosis)

  • Blurred or double vision (diplopia)

  • Difficulty chewing, swallowing, or speaking

  • Weakness in arms, legs, neck, or breathing muscles

  • Fatigue that increases throughout the day

  • Shortness of breath in severe cases

Causes and triggers:

  • Autoimmune attack on acetylcholine receptors

  • Thymus gland abnormalities (including thymoma)

  • Illness, stress, heat, or certain medications can trigger flare-ups

When to see a doctor:
Seek medical attention if you experience sudden or unexplained muscle weakness, especially involving the eyes, face, or breathing. Diagnosis involves antibody blood tests, electromyography (EMG), edrophonium test, and imaging of the thymus. Treatment may include acetylcholinesterase inhibitors, corticosteroids, immunosuppressants, IVIG, or plasmapheresis.

Natural remedies for Myasthenia Gravis

Take Frequent Rest Breaks: Helps manage fatigue and conserve energy.

Eat Smaller, Softer Meals: Reduces effort during chewing and swallowing.

Use Adaptive Devices: Mobility aids, utensils, or braces to conserve strength.

Avoid Overheating and Stress: Both can worsen symptoms.

Monitor Medications Carefully: Some drugs can exacerbate MG—always consult a physician.