Evidence supporting the use of: Vitamin D3
For the health condition: Menopause

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin D3 is used to support menopausal health primarily on the basis of scientific rationale, although the strength of evidence is modest. During menopause, declining estrogen levels contribute to an increased risk of osteoporosis and decreased bone mineral density. Vitamin D3 (cholecalciferol) plays a critical role in calcium absorption and bone metabolism. Several guidelines recommend ensuring adequate vitamin D status in peri- and postmenopausal women to maintain bone health and reduce the risk of fractures. Clinical studies demonstrate that low vitamin D levels are common in postmenopausal women and are associated with greater bone loss and higher fracture risk.

However, randomized controlled trials examining vitamin D supplementation in menopausal women have shown mixed results regarding its ability to reduce fracture risk or improve bone mineral density independently of calcium. Most benefits are observed when vitamin D3 is combined with calcium supplementation. There is limited evidence that vitamin D3 alone alleviates other menopausal symptoms such as hot flashes, mood changes, or sleep disturbances.

In summary, the use of vitamin D3 during menopause is scientifically justified for maintaining bone health and preventing osteoporosis, especially in women with inadequate levels. Its role in managing other menopausal symptoms is not well established. The evidence supports its use mainly for bone-related outcomes, earning a moderate evidence score.

More about vitamin D3
More about Menopause

Other ingredients used for Menopause

27-deoxyactein
7-hydroxymatairesinol (HMR)
8-Prenylnaringenin
Achyranthes
Agnuside
Agrimonia pilosa
Akebia
Alchemilla
Alfalfa
Aloe vera
amaranth
Anemarrhena
anemarrhena asphodeloides
antler
Ashoka
ashwagandha
asparagus
astragalus
atractylodes
atractylone
banyan
barrenwort
bee pollen
bioflavonoids
black cohosh
black currant
black root
black seed
bupleurum falcatum
burdock
calcium
chaste tree
Chinese silkvine
Clary sage
Cnidium
cohosh
cordyceps
Crinum latifolium
Cynomorium
daidzein
damiana
danshen
DHEA
DHEA (dehydroepiandrosterone)
DIM (diindolylmethane)
dioscorea
dog rose
dong quai
dong quai root
durian
eleuthero
elk antler
equol (proprietary)
estrogen
Euryale seed
evening primrose oil
evening primrose oil
fenugreek
Ficus religiosa
fish oil
flaxseed
fo-ti
genistein
genistin
Glycetein
goji berry
hibiscus
HMR lignan
hops
horny goat weed
Hypericum
Indian frankincense
isoflavones
jujube
knotweed
kudzu
Labisia pumila
Lady's Mantle
lemon balm
licorice root
lignans
linden
lingzhi
Loranthus
lotus
Lycium
maca
macaenes
macamides
Marine lipid
Meadow sage
Melatonin
Miroestrol
Montanoa tomentosa
Moringa
Motherwort
Nettle
okra
omega-3 fatty acids
Ophiopogon
ophiopogon root
Phytoestrogens
pollen
Polygonum
pomegranate
Prickly Pear Cactus
Puerain
Pulsatilla
red clover
Rehmannia
rehmannia glutinosa
reishi mushroom
rhubarb
rockweed
Rooibos
root tuber
Rosa laevigata
rose
rose oil
royal jelly
Rubia cordifolia
Rubus
rue
saffron
sage
seaweed
smilax
Soy
soy isoflavones
Soy Protein
soybean
Stone Root
Valerian root
Vervain
Viburnum
vitamin B6
vitamin D
vitamin D3
vitamin E
Vitex Agnus-Castus
Wild yam
Withanolides
Yellow-Fruit Nightshade