Synopsis

Source of validity: Scientific
Rating (out of 5): 3

St. John's Wort (Hypericum perforatum) has a long history of traditional use, particularly in Europe, for treating various mood disorders. However, its use for "mood swings" specifically is less well established than its use for mild to moderate depression. The scientific evidence for St. John’s Wort primarily centers on its efficacy in depressive symptoms, not mood swings per se (such as those seen in bipolar disorder or premenstrual syndrome). Numerous randomized, placebo-controlled trials and meta-analyses have demonstrated that St. John's Wort can be more effective than placebo and as effective as some standard antidepressants in treating mild to moderate depression. The herb is believed to work by influencing neurotransmitters like serotonin, dopamine, and norepinephrine in the brain.

While some people use St. John’s Wort to help regulate mood fluctuations, the direct evidence supporting its use specifically for mood swings is limited. There is a lack of robust clinical trials addressing its efficacy for mood instability outside of depressive disorders. Importantly, St. John’s Wort can interact with many medications and may trigger manic episodes in individuals with bipolar disorder.

In summary, while scientific evidence supports St. John’s Wort for depressive symptoms, its use for mood swings is less substantiated and should be approached with caution. Always consult a healthcare provider before use, especially if you have mood disorders or are taking other medications.

More about St. John's Wort
More about Mood Swings

Other ingredients used for Mood Swings

Other health conditions supported by St. John's Wort

Products containing St. John's Wort

Nature's Sunshine St. John's Wort (Concentrated)
Nature's Sunshine St. John's Wort (Concentrated Time Release)