Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Silicone is widely used for the treatment of scars and scar tissue, and its use is strongly supported by scientific evidence. Silicone gel sheets and silicone-based topical gels have become standard recommendations for the management of hypertrophic scars and keloids. The first clinical use of silicone sheeting for scars was reported in the early 1980s, and since then, numerous randomized controlled trials and meta-analyses have confirmed its efficacy.

Silicone works through several mechanisms: it creates a protective barrier over the skin, increases hydration of the stratum corneum, and modulates fibroblast production, which can reduce collagen production and scar formation. Studies show that silicone sheeting and gels can significantly improve scar color, texture, and height, especially when used on new scars. Meta-analyses published in Plastic and Reconstructive Surgery and the Cochrane Database have found that silicone products are among the most effective non-invasive treatments for hypertrophic and keloid scars.

Silicone is safe, non-invasive, and well-tolerated, with minimal side effects. It is recommended by many dermatologists and plastic surgeons for both prevention and treatment of abnormal scars. While not all scars will respond completely, the overall body of scientific evidence supports the use of silicone as a first-line treatment for scar management.

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