Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Osthole is a natural coumarin compound primarily extracted from the fruit of Cnidium monnieri, a plant widely used in Traditional Chinese Medicine (TCM). Historically, Cnidium monnieri and its extract, osthole, have been used in TCM formulations for the treatment of various ailments, including those related to pain and inflammation, such as neuralgia (nerve pain) and neuritis (nerve inflammation). The traditional use is based on the TCM principle of dispelling wind and dampness and promoting blood circulation, which are believed to help alleviate pain syndromes. From a scientific perspective, there is limited but growing preclinical evidence indicating that osthole exerts anti-inflammatory, analgesic, and neuroprotective effects. Some animal studies suggest that osthole may reduce neuroinflammation and oxidative stress, which are relevant mechanisms in neuralgia and neuritis. However, robust clinical trials or high-quality human studies directly evaluating osthole for neuralgia or neuritis are lacking. Most evidence comes from cell culture or animal research, and there are no established clinical guidelines supporting its use for these specific neurological conditions. In summary, the use of osthole for neuralgia and neuritis is primarily justified by traditional medicinal practices, with some preliminary scientific exploration but insufficient evidence to firmly validate its effectiveness in humans for these indications.

More about Osthole
More about Neuralgia and Neuritis

Other ingredients used for Neuralgia and Neuritis

Other health conditions supported by Osthole

Products containing Osthole