Evidence supporting the use of: Licorice (unspecified)
For the health condition: Urinary Tract Infections

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Licorice (Glycyrrhiza glabra) has a long history of use in traditional medicine systems, including Traditional Chinese Medicine (TCM) and Ayurveda. In these traditions, licorice is valued for its anti-inflammatory, demulcent, and antimicrobial properties, and is sometimes included in formulations intended to support the urinary tract or soothe urinary discomfort. However, there is limited direct historical reference to licorice being used specifically for the treatment of urinary tract infections (UTIs) as a primary indication. More commonly, licorice is used for respiratory, digestive, and inflammatory conditions.

From a scientific perspective, laboratory studies have demonstrated that licorice contains compounds (such as glycyrrhizin) with antimicrobial and anti-inflammatory effects. Some in vitro research suggests that licorice extracts may inhibit the growth of certain bacteria, including Escherichia coli, which is a common cause of UTIs. However, clinical trials specifically assessing licorice as a treatment for UTIs in humans are lacking. The evidence primarily consists of preclinical data and historical use, rather than robust human studies.

In summary, licorice is used traditionally in herbal medicine, sometimes within formulas aimed at urinary health, but there is minimal direct scientific or clinical evidence to support its use for UTIs. The evidence rating is low due to the lack of targeted clinical research.

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