Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Khella (Ammi visnaga) has a long history of traditional use, particularly in Middle Eastern and Mediterranean herbal medicine, for the support and relief of angina and other cardiovascular complaints. The seeds contain active compounds such as khellin and visnagin, which are known to exert vasodilatory effects, especially on the coronary arteries. Historically, these properties led to its use as a folk remedy for angina pectoris prior to the advent of modern pharmaceuticals.

While some early pharmacological studies conducted in the mid-20th century demonstrated that khellin could dilate coronary arteries and potentially reduce the frequency of anginal attacks, clinical evidence remains limited. Modern clinical trials are scarce, and the existing studies are small and often methodologically weak by today’s standards. Khella and its derivatives have largely been replaced by more effective and safer drugs such as nitrates and calcium channel blockers.

In summary, the use of Khella for angina is primarily grounded in traditional practice with some historical pharmacological rationale. However, robust scientific validation is lacking, and its use today is rare and not widely recommended in conventional medicine. The evidence supporting its efficacy for angina is modest at best and does not meet current standards for clinical endorsement.

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