Homalomena species, particularly Homalomena aromatica and Homalomena occulta, have a history of use in traditional medicine systems across Asia, including Ayurveda and Traditional Chinese Medicine (TCM). In these practices, the plant is sometimes employed as part of herbal formulations used to address liver ailments, including jaundice in adults. The rationale behind its use is typically based on its perceived properties for "cooling" the body, detoxifying effects, and supporting liver function. However, there is a lack of robust clinical or pharmacological studies specifically validating the efficacy or safety of Homalomena for jaundice in adults. Most available information is anecdotal or derived from ethnobotanical surveys. The limited laboratory research that exists focuses mainly on anti-inflammatory or antimicrobial effects and does not directly address jaundice or liver function restoration. Therefore, while its use is grounded in tradition, the scientific evidence supporting its use for jaundice is very weak, and it is not recognized in evidence-based medical guidelines for this condition.