Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Glutamine is an amino acid that has been studied for its role in supporting mucosal healing, including ulcerations. While most research focuses on gastrointestinal (internal) ulcerations—such as those in the mouth (oral mucositis) or gut (peptic ulcers)—some evidence extends to external ulcerations, like skin wounds and pressure ulcers. Glutamine is believed to support tissue repair processes due to its role in cellular proliferation, immune function, and as a nitrogen donor for rapidly dividing cells. Several small clinical trials and animal studies have explored topical or oral glutamine supplementation for wound healing. Some studies have shown favorable effects, such as improved healing rates and reduced inflammation in pressure ulcers and burns, particularly in malnourished or critically ill patients. However, results are inconsistent, sample sizes are small, and methodological quality varies, leading major clinical guidelines to stop short of broadly recommending glutamine for external ulcerations. The evidence is therefore considered limited but suggestive. Glutamine has not been a major part of traditional wound care in most cultures, and its modern use is based on emerging clinical science rather than long-standing historical practice. Further high-quality, large-scale randomized controlled trials are needed to clarify glutamine’s role in managing external ulcerations.

More about Glutamine
More about Ulcerations (external)

Other ingredients used for Ulcerations (external)

Other health conditions supported by Glutamine

Products containing Glutamine