Evidence supporting the use of: Capsiate
For the health condition: Weight Loss
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Capsiate is a non-pungent analog of capsaicin, naturally found in "CH-19 Sweet" peppers. Its primary use in weight loss is supported by scientific evidence, mainly from animal studies and a limited number of human trials. Capsiate has been shown to increase energy expenditure and fat oxidation through stimulation of the sympathetic nervous system, similar to capsaicin but without the spicy sensation. Several randomized, placebo-controlled trials in humans have demonstrated modest increases in resting metabolic rate and fat oxidation after capsiate supplementation, with daily doses ranging from 3-9 mg. However, the observed effects on actual weight loss are generally small and may not reach clinical significance in the short term.
Meta-analyses and systematic reviews suggest that capsiate can lead to a slight increase in calorie burning (about 50 kcal/day), which could contribute to weight control over time if maintained. The European Food Safety Authority (EFSA) recognizes these metabolic effects but considers the evidence insufficient for health claims related to weight loss in the general population. Side effects are minimal, and the compound is generally well tolerated.
In summary, there is scientific evidence supporting capsiate's thermogenic and fat oxidation effects, but the magnitude of weight loss is modest. More long-term and large-scale clinical trials are needed to confirm its efficacy for weight reduction in diverse populations.
Other ingredients used for Weight Loss
1,3,7-Trimethylpurine-2,6-dione3-desoxy-7-KETO-DHEA
7-Keto-DHEA
Acetyl L-carnitine
Adrenergic amines
Adzuki bean
Akkermansia muciniphila
Algae
Algal protein
Almond fruit
alpha-ketoglutarate (AKG)
amaranth
AMP-activated protein kinase (AMPK)
animal protein
apple
Ascophyllum nodosum
ashwagandha
BCAA
bean
Beef Protein
beta-hydroxybutyrate
black ginger
black tea
brown rice protein
California chia
capsiate
capsinoids
Caralluma fimbriata
cardarine
cha de bugre
chia seed
chickpea protein
chlorogenic acid
cocoa
Coleus forskohlii
conjugated linoleic acid (CLA)
cowpea
deoxycholic acid
diacylglycerol
dihydrocapsiate
ecdysteroids
egg
ephedrine
evodiamine
fish
forskohlii root
forskolin
Foxtail millet
fucoxanthin
garbanzo bean
garcinia
glucomannan
grains of paradise
guarana
Guaranine
Gymnema
HMB hydroxymethylbutyrate
Hoodia
hydroxycitric acid
hydroxymethylbutyrate
inulin
Irvingia gabonensis
isomaltulose
jiaogulan
kidney beans
Konjac
L-leucine
Legume protein
Matcha
Mate
medium chain triglycerides (MCT)
millet seed
Monkfruit
Oleoylethanolamide
oolong tea
Palatinose
phaseolamin
Pistachio
polychitosamine
Propolmannan
prune
purple tea
pyruvate
quinoa
Quinoa Protein
Rauwolscine
robusta coffee
rye
saffron
soybean
Steviol glycosides
Synephrine
Thylakoid
Tiger Nut
Vegetable Protein
Whey protein
Xanthohumol
Yacon
Yerba mate
Yohimbine
Other health conditions supported by capsiate
Athletic and Exercise AidsBody Building
Fat Metabolism (poor)
Metabolic Syndrome
Triglycerides (high)
Weight Loss
