Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Calotropis gigantea, also known as crown flower or giant milkweed, has a long history of traditional use in Ayurvedic and folk medicine, including applications for skin ailments such as wounds, ulcers, and scars. Its latex, leaves, and extracts have been topically applied in various cultures to support the healing of skin tissue and potentially reduce the appearance of scars. The rationale in traditional medicine is often based on its perceived anti-inflammatory, antimicrobial, and wound-healing properties.

Modern scientific studies specifically evaluating Calotropis gigantea for the treatment of scars or scar tissue are limited. However, a few preclinical studies suggest that extracts of this plant can promote wound healing and exhibit antimicrobial activity, which are potentially relevant to the process of scar formation and remodeling. For example, some animal studies have shown that topical application of Calotropis gigantea leaf extract can accelerate wound contraction and epithelialization. Despite these findings, direct clinical evidence for its effectiveness in scar reduction or scar tissue remodeling in humans is lacking.

In summary, while the use of Calotropis gigantea for scars is rooted in traditional medicine, and there is some preclinical evidence suggesting wound-healing potential, robust scientific validation—especially in the context of scar treatment in humans—is currently insufficient.

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