Evidence supporting the use of: Vitamin D
For the health condition: Hypertension

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin D has been investigated as a potential supportive agent in the management of hypertension due to its role in calcium metabolism and vascular health. Epidemiological studies have shown that low serum levels of vitamin D are associated with increased risk of hypertension and cardiovascular disease. Mechanistically, vitamin D is thought to modulate the renin-angiotensin-aldosterone system (RAAS), which plays a central role in blood pressure regulation. Vitamin D deficiency may lead to increased renin secretion, resulting in higher blood pressure.

However, interventional studies and randomized controlled trials (RCTs) have produced mixed results. Some smaller studies and meta-analyses suggest a modest blood pressure-lowering effect of vitamin D supplementation, particularly in individuals who are vitamin D deficient or have pre-existing hypertension. For example, a 2019 meta-analysis in the Journal of Human Hypertension reported a slight reduction in systolic blood pressure with vitamin D supplementation, though the effect was small and not consistently observed across all studies.

Overall, the evidence does not robustly support vitamin D supplementation as an effective standalone treatment for hypertension in the general population. Major guidelines do not recommend vitamin D solely for blood pressure control, but it may be considered in individuals with confirmed deficiency. The evidence base is rated as weak to moderate (2/5), largely due to inconsistent findings and small effect sizes.

More about vitamin D
More about Hypertension

Other ingredients used for Hypertension

Acai berry
Adzuki bean
Alfalfa
Algae
algal oil
Algal protein
Alisma
Allicin
Alliin
Almond fruit
alpha-linolenic acid (ALA)
alpha-lipoic acid
amaranth
AMP-activated protein kinase (AMPK)
ampelopsin
anthocyanidins
anthocyanins
anthocyanosides
apigenin
argan nut oil
Arginine silicate
arjun tree
arjuna
arjunic acid
Arjunolic acid
Aronia melanocarpa
arugula
Ascophyllum nodosum
ashitaba
ashwagandha
asparagus
astaxanthin
astragalin
astragaloside
astragalus
Auricularia
Autumn Olive
avocado
bael
baicalein
baicalin
banaba
banana
barbasco
barley
Bassia scoparia
Bauhinia
bayleaf
beet
berberine
bergamot
beta caryophyllene
beta-glucan
betanin
bignay
bilberry
black cumin
black currant
black garlic
black ginger
black seed
black tea
blackberry
blackboard tree
Blue-Green Alage
blueberry
bok choy
Bombax
bonito peptide
Borassus aethiopum
bottle gourd
Brassica
Brazil nut
breadnut
broccoli
Broussonetia
Brown Algae
Brussel sprouts
brutieridin
Buckwheat
bupleurum falcatum
C-phycocyanin
caffeic Acid
calcium
California chia
Camellia sinensis
cantaloupe
capers
capsicum
carambola
cassava
cat's claw
catalpol
catechins
caterpillar mushroom
catjang cowpea
cauliflower
celery
cha de bugre
cherimoya
cherry
chia seed
chia seed
chickpea protein
Chinese fleeceflower
Chinese Ligustrum berry
Chinese salvia root
Chinese silkvine
chive
chlorella
chlorogenic acid
Chlorophytum
chocolate
chokeberry
chrysanthemum
cinnamon
cistanche
citrus bioflavonoids
citrus sinensis (proprietary)
Clerodendrum indicum
cocoa
Coconut Water
cod liver oil
coenzyme Q10 (CoQ10)
coix
Coleus forskohlii
collard
cowpea
crocetin
cruciferous
cucumber
currant
cyanobacteria
Cyclanthera pedata
daidzein
daidzin
danshen
date
diallyl disulfide (DADS)
diallyl trisulfide (DATS)
dioscorea
dragon fruit
Ecklonia
eggplant
eicosapentaenoic acid
eleuthero
emblicanin
EPA (eicosapentaenoic acid)
epicatechin
epigallocatechin gallate (EGCG)
eriocitrin
eucommia
Eucommia ulmoides
Fagopyrum
ferulic acid
fiber
Ficus religiosa
Ficus simplicissima
fig
fish
fish oil
fish protein
Flammulina velutipes
flavanols
flavanones
flavans
flavones
flavonones
flaxseed
Flueggea suffruticosa
fo-ti
forskohlii root
Foxtail millet
fruit and vegetable blend (proprietary)
gallic acid
ganoderma
garbanzo bean
garden cress
Ginsenosides
Glucan peptides
Glycine
Glycosylsteviosides
goji berry
gooseberry
gotu kola
grape
green tea
greens blend (proprietary)
Gypenoside
hawthorn
hazelnut
hesperetin
hesperidin
hibiscus
horse gram
hydroxycinnamic acid
hydroxytyrosol
Hygrophila
icariin
inula racemosa
iridoids
Irvingia gabonensis
isoflavones
isoleucyl-prolyl-proline
isoliquiritigenin
Jaboticaba
Java tea
jiaogulan
Jicama
Job\'s tears
jujube
Kaempferol
kale
Kamut
Kefir
Khella
kidney beans
kiwi
Konjac
kucha tea
kuding tea
kudzu
Kumquat
L-arginine
L-citrulline
L-taurine
lactium casein decapeptide
Lactobacillus gasseri
Lactobacillus helveticus
Lactotripeptides
Legume protein
Lentil
Lentinula edodes mycelia
ligustilides
linden
lingzhi
linoleic acid (LA)
Litsea
longan
loquat
Loranthus
lotus
lotus seed
lupin
luteolin
Lycium
lycopene
macadamia
magnesium
magnolol
maitake mushroom
mangiferin
mango
mangostene xanthone
Marine fat
Marine lipid
Marine protein
Matcha
Mealy Kudzu
Melatonin
Melon
Milk Protein
Millet
millet seed
Mistletoe
Monounsaturated fat
Moringa
Morus
Motherwort
Mulberry
Naringenin
Naringin
Nattokinase
Nettle
noni
Nori
oat
okra
oleanolic acid
oleic acid
Oleoperin
Oleuropein
Oligomeric proanthocyanidins
olive
omega-3 fatty acids
omega-9 fatty acids
oolong tea
Ophiopogon
ophiopogon root
orange
Oroxylum indicum
Osmanthus
Osthole
oyster mushroom
paeoniflorin
pantethine
Passionfruit
Pasuchaca
Patrinia
perilla
Persimmon
Phaeophyceae
Phellodendron
phlorotannins
Phthalides
Phycocyanin
Phytoestrogens
pine bark
Pleurotus eryngii
Plukenetia volubilis
plum fruit
Polydatin
Polygonatum
Polygonum
pomegranate
pomelo
potassium
prebiotic blend (proprietary)
Prickly Pear Cactus
proanthocyanidins
procyanidin
psyllium
pu-er tea
Puerain
Puerarin
punicalagins
purple tea
purslane
Pycnogenol
quail egg
quercetin
quinoa
Quinoa Protein
radish
rapeseed oil
Rauvolfia
red yeast
red yeast rice
Rehmannia
rehmannia glutinosa
reishi mushroom
resveratrol
rice
Rooibos
Rosa roxburghii
rosmarinic acid
rosthorn snake gourd
Rubiaceae
Rutaecarpine
rutin
rye
S-allylcysteine
Sacha Inchi
safflower oil
saffron
Salidroside
Salvianolic acid
Sandalwood
Schizochytrium Oil
Scoparia dulcis
Scopoletin
Scotch Broom
seaweed
Semecarpus anacardium
sesame
Sesamin
shiitake mushroom
Shilajit
Solanum anguivi
soursop
Soy
soy isoflavones
Soy Protein
soybean
spinach
spirulina
Steviol glycosides
Stevioside
strawberry
sunflower
Tamarind
Tanshinone
Taurine
Taxifolin
Taxillus chinensis
Tejocote
Theabrownin
Theaflavin
Thylakoid
Tiger Nut
Tinospora cordifolia
tocotrienols
Tremella
Tribuloside
Tropical jewel hisbiscus
ubiquinol
Valyl-Prolyl-Proline
vegetable and fruit blend (proprietary)
vegetable blend (proprietary)
vegetable oil
Vegetable Protein
Vine tea
vitamin C
vitamin D
vitamin D3
Vitexin
Wakame
Walnut
Watermelon
Wax Gourd
White Tea
Winter Begonia
Withanolides
Xanthone
Xanthophyll
Xantinol Nicotinate
Yuzu
Zapilopatle Bean
Zucchini

Other health conditions supported by vitamin D

Acne
Allergies (food)
Allergies (respiratory)
Alzheimer's Disease
Amenorrhea
Anemia
Anorexia
Apathy
Arrhythmia
Arteriosclerosis
Arthritis
Asthma
Autism
Autoimmune Disorders
Backache
Birth Defects (prevention)
Body Building
Broken Bones
Calcium Deficiency
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Cardiovascular Disease
Celiac Disease
Chronic Obstructive Pulmonary Disorder
Colds (antiviral)
Colds (general)
Colds (prevention)
Colds (with fever)
Concentration (poor)
Concussions
Confusion
Congestive Heart Failure
Contagious Diseases
Convalescence
Convulsions
Cramps (menstrual)
Cramps and Spasms
Crohn's Disease
Cystic Breast Disease
Cystic Fibrosis
Dandruff
Debility
Dementia
Depression
Dermatitis
Diabetes
Diabetic Retinopathy
Erectile Dysfunction
Estrogen (low)
Fatigue
Fibroids (uterine)
Fibromyalgia Syndrome
Fibrosis
Grave's Disease
Grief and Sadness
Hair (loss or thinning)
Hair Care (general)
Hashimoto's Disease
Headache (cluster)
Heart (weakness)
Hypertension
Hypothyroid
Infection
Infection (bacterial)
Infection (viral)
Infertility
Inflammation
Inflammatory Bowel Disorders
Influenza
Injuries
Irritable Bowel Syndrome
Itching
Knees (weak)
Leaky Gut Syndrome
Leprosy
Lesions
Leukemia
Lou Gehrig's Disease
Lupus
Lymphoma
Melanoma
Memory and Brain Function
Menopause
Menstrual Irregularity
Mental Illness
Metabolic Syndrome
Migraine
Miscarriage (prevention)
Mood Swings
Multiple Sclerosis
Muscle Tone (lack of)
Muscular Dystrophy
Myasthenia Gravis
Nephritis
Nerve Damage
Nervous Exhaustion
Numbness
Nursing
Obsessive Compulsive Disorder
Oral Surgery
Osteoporosis
Pain (general remedies for)
Pancreatitis
Paralysis
Parkinson's Disease
Peripheral Neuropathy
PMS (general)
PMS Type D
PMS Type H
PMS Type P
PMS Type S
Pneumonia
Polyps
Post Partum Depression
Post Partum Weakness
Pregnancy (herbs and supplements for)
Progesterone (low)
Prostatitis
Psoriasis
Rheumatoid Arthritis
Schizophrenia
Sciatica
Seasonal Affective Disorder
Senility
Tuberculosis