Evidence supporting the use of: Coenzyme Q10 (CoQ10)
For the health condition: Arteriosclerosis

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Coenzyme Q10 (CoQ10) is supported by some scientific evidence for use in cardiovascular conditions, including arteriosclerosis (hardening and narrowing of the arteries), though the strength of the evidence is moderate and not conclusive. CoQ10 is an endogenous antioxidant involved in mitochondrial energy production. Oxidative stress and endothelial dysfunction are key factors in the development and progression of arteriosclerosis, and CoQ10’s antioxidant properties are thought to help mitigate these processes.

Several clinical studies have shown that CoQ10 supplementation can improve endothelial function, reduce oxidative stress, and lower blood pressure—factors relevant to arterial health. Some trials suggest that CoQ10 may decrease arterial stiffness and improve lipid profiles, both of which are important in arteriosclerosis. A 2018 meta-analysis published in Atherosclerosis found that CoQ10 supplementation significantly improved endothelial function in patients with cardiovascular diseases. However, most studies are small, short-term, and often include patients with a mix of cardiovascular disorders, making results less specific to arteriosclerosis itself.

Overall, while there is scientific rationale and some clinical data supporting the use of CoQ10 for arteriosclerosis and related cardiovascular conditions, the quality and quantity of evidence are not strong enough for it to be considered a primary or standalone treatment. It is generally used as an adjunct to established therapies. More large-scale, long-term trials are needed to clarify its role in arteriosclerosis management.

More about coenzyme Q10 (CoQ10)
More about Arteriosclerosis