Evidence supporting the use of: Phosphocreatine
For the body system: Muscles
Synopsis
Source of validity: Scientific
Rating (out of 5): 5
Phosphocreatine is scientifically validated as a key component in muscle energy metabolism, particularly during short bursts of high-intensity activity. In muscle cells, phosphocreatine serves as a rapidly mobilizable reserve of high-energy phosphates. When muscles contract, adenosine triphosphate (ATP) is broken down to provide energy. However, ATP stores are limited and depleted quickly during intense activity. Phosphocreatine donates a phosphate group to adenosine diphosphate (ADP) to rapidly regenerate ATP, helping to sustain muscular contraction and delay fatigue.
Numerous clinical studies support the effectiveness of creatine supplementation (which increases muscle phosphocreatine stores) in enhancing performance in activities involving repeated bouts of high-intensity exercise, such as weight lifting and sprinting. Meta-analyses and systematic reviews consistently show improvements in maximal strength, power output, and lean muscle mass with creatine supplementation. The International Society of Sports Nutrition and other expert bodies recognize creatine (and by extension, its role in phosphocreatine metabolism) as one of the most effective and well-researched ergogenic aids available for athletes and physically active individuals.
In summary, the use of phosphocreatine to support the muscle system is rooted in strong scientific evidence, with well-established mechanisms of action and reproducible benefits demonstrated in numerous human trials.
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Alpha hydroxyisocaproic acid
alpha-ketoglutarate (AKG)
Alpha-ketoisocaproic acid
amino acids
AMP-activated protein kinase (AMPK)
animal protein
animal Tissue
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arachidonic acid
arginine alpha ketoglutarate
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Arginine aspartate
arginine creatine
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arnica
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astaxanthin
avocado
ba ji tian
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BCAA
bee products
beef
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beet
beta-alanine
beta-hydroxybutyrate
bicarbonate
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black galingale
black ginger
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blue cohosh
bovine
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bovine protein
branched-chain amino acids
bromelain
brown rice protein
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caffeine
calcium
camphor oil
cardarine
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casein
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cherry
chia seed
chickpea protein
Chinese mountain ant
chloride
chuchuhuasi
citrate malate
coca
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coenzyme Q10 (CoQ10)
colostrum
conjugated linoleic acid (CLA)
cordyceps
cramp bark
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d-alpha tocopherol
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date
deer velvet
devil's claw
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dong quai root
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elk antler
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epicatechin
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guanidinopropionic acid (GPA )
guelder rose
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l-carnitine
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phosphorus
phytocannabinoids
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protein
proteolytic enzymes
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rhizome
ribose
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soybean
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squawvine
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turmeric
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ubiquinol
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