Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Melatonin is a hormone primarily produced by the pineal gland in the brain and is best known for its role in regulating circadian rhythms and sleep-wake cycles. Its use to support the glandular system is scientifically justified, as the pineal gland is an integral part of this system. Numerous studies have documented that endogenous melatonin production declines with age and that supplementation can help restore normal sleep patterns in individuals with circadian rhythm disorders or insomnia. Beyond sleep regulation, melatonin also exhibits regulatory effects on other endocrine glands, influencing hormones such as cortisol and reproductive hormones through its interactions with the hypothalamic-pituitary axis. Additionally, melatonin acts as a potent antioxidant and modulator of immune function, which are activities relevant to glandular health. There is ongoing research into its protective effects on the thyroid, pancreas, and reproductive glands. Most of the scientific validation centers on its role in synchronizing circadian and hormonal rhythms rather than directly supporting or “strengthening” all glands. While the majority of evidence supports melatonin’s impact on the pineal and indirectly on other glands, there is robust scientific consensus for its use in regulating glandular function primarily through circadian modulation and neuroendocrine effects.

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Products containing Melatonin

Nature's Sunshine Melatonin Extra