Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Flavones, a class of plant-derived polyphenolic compounds found in foods such as parsley, celery, and chamomile, have demonstrated some scientific support for their role in supporting capillary health. Flavones, particularly diosmin and hesperidin (often referred to as "citrus flavonoids"), have been studied for their vascular protective effects. Research indicates that these compounds can strengthen capillary walls, reduce capillary permeability, and improve microcirculation. For example, clinical studies on patients with chronic venous insufficiency and related capillary fragility have shown that flavone-rich extracts can decrease edema, reduce symptoms such as leg heaviness, and decrease bruising by stabilizing capillary membranes and inhibiting inflammatory mediators. The proposed mechanisms include antioxidant activity, inhibition of enzymes that degrade capillary integrity (such as hyaluronidase), and modulation of vascular tone. However, most studies involve specific flavones (like diosmin or hesperidin) rather than the entire class, and some positive results come from combination products, making it difficult to assign effects solely to flavones. The overall evidence is moderate, with several randomized controlled trials and mechanistic studies supporting their benefit, but further research is needed to determine the efficacy and optimal dosing of flavones for capillary health in the general population.

More about flavones
More about Capillaries

Other ingredients that support Capillaries

Other body systems supported by flavones

Products containing flavones