Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Convolvulus pluricaulis, commonly known as Shankhpushpi, is a traditional herb used predominantly in Ayurvedic medicine. Its use is primarily justified by historical and traditional practice rather than robust scientific validation. In Ayurveda, Shankhpushpi is considered a "medhya rasayana," or a cognitive enhancer, and is traditionally employed to support mental health, including stress, anxiety, and memory-related concerns. These effects are sometimes attributed to its potential influence on neurotransmitters, including serotonin, but direct evidence supporting this mechanism is limited. A few animal studies have suggested that extracts of Convolvulus pluricaulis may have anxiolytic and antidepressant-like effects, which could imply a modulatory effect on the serotonergic system. For instance, some preclinical research indicates possible enhancement of brain serotonin levels and inhibition of monoamine oxidase, an enzyme involved in neurotransmitter breakdown. However, these studies are preliminary, often conducted in rodents, and do not provide definitive evidence for its efficacy or mechanism in humans. There are no large-scale, high-quality clinical trials confirming that Convolvulus pluricaulis directly supports serotonin levels or the serotonin system in humans. Therefore, while its traditional use for supporting mental health is well-established, the specific connection to serotonin remains speculative and largely unproven in scientific literature.

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