Evidence supporting the use of: Gotu kola
For the body system: Veins

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Gotu kola (Centella asiatica) has a long history of use in traditional medicine systems, such as Ayurveda and Traditional Chinese Medicine, for supporting vascular health and wound healing. In modern times, its use for the "Veins" body system—particularly for chronic venous insufficiency (CVI) and varicose veins—has been investigated in several clinical and preclinical studies.

Some randomized controlled trials and reviews have shown that triterpenoid compounds in gotu kola (notably asiaticoside and madecassoside) can improve microcirculation, reduce capillary permeability, and enhance venous tone. For example, a 2001 review in Angiology summarized clinical trials where gotu kola extracts led to improvements in leg edema and symptoms of CVI compared to placebo. Another systematic review (Phytomedicine, 2013) found moderate evidence supporting its efficacy for venous insufficiency, though the number and size of high-quality studies remain limited.

Mechanistically, gotu kola is thought to strengthen connective tissue in blood vessel walls, reduce inflammation, and promote collagen synthesis. These actions may help relieve symptoms such as swelling, heaviness, and discomfort in the legs.

While the evidence base is not as robust as for pharmaceutical treatments, the use of gotu kola for venous health is supported by both traditional usage and moderate scientific validation, especially for mild to moderate cases of venous insufficiency. More large-scale, high-quality clinical trials are needed to confirm its effectiveness and safety profile.

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