Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Pine bark extract, particularly from the French maritime pine (Pinus pinaster), is widely used to support vein health, especially in the context of chronic venous insufficiency (CVI) and related vascular issues. The scientific foundation for this use comes primarily from studies on Pycnogenol®, a standardized extract of pine bark. Clinical trials have demonstrated that Pycnogenol® can improve symptoms of CVI—such as leg swelling, heaviness, and edema—by enhancing venous tone and supporting microcirculation. The mechanism appears to involve its potent antioxidant and anti-inflammatory properties, as well as improvement in capillary permeability and integrity.

Meta-analyses and randomized, placebo-controlled trials have found that supplementation with pine bark extract leads to significant reductions in leg swelling and discomfort in patients with venous disorders. For example, a 2012 review in “Phytotherapy Research” concluded that Pycnogenol® is effective in reducing symptoms of CVI and improving overall venous function. The extract has also been observed to reduce the risk of deep vein thrombosis during long-haul flights.

The evidence is not limited to anecdotal or traditional use but is supported by a moderate to robust body of clinical data, justifying a high evidence rating. However, while the effects are consistently positive, some studies are small and further large-scale research would be beneficial for solidifying recommendations.

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