Evidence supporting the use of: Lipase
For the body system: Gall Bladder

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Lipase is an enzyme that plays a central role in the digestion of dietary fats. The gallbladder itself does not produce lipase; rather, it stores and concentrates bile produced by the liver, which is then released into the small intestine to emulsify fats and facilitate their digestion by enzymes such as lipase (primarily pancreatic lipase). Supplemental lipase is sometimes used to support fat digestion in individuals with compromised pancreatic or digestive function, such as those with pancreatic insufficiency or cystic fibrosis. Scientific studies indicate that supplemental lipase can improve fat absorption in these populations.

However, direct evidence supporting the use of lipase specifically to “support the gallbladder” is limited. The gallbladder’s main function is related to bile storage and release; it is not directly involved in enzyme production. Some supplement protocols include lipase for general support of fat digestion, which can indirectly reduce the workload on the gallbladder by improving fat breakdown and absorption. This may be beneficial in cases of gallbladder dysfunction or after gallbladder removal, but robust clinical trials specific to gallbladder health are lacking.

In summary, while there is scientific evidence for lipase supplementation in supporting fat digestion, its use for direct gallbladder support is based more on the relationship between fat digestion and gallbladder function rather than direct clinical evidence targeting the gallbladder itself.

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