Green-lipped mussel (perna canaliculus)
Synopsis of green-lipped mussel
Green lipped mussel (Perna canaliculus) is a species of shellfish native to the coastal waters of New Zealand, named for the distinctive green edge on its shell. It is prized in nutritional and integrative medicine for its rich content of omega-3 fatty acids (especially EPA and DHA), glycosaminoglycans (like chondroitin sulfate), amino acids, minerals (zinc, selenium), and unique anti-inflammatory compounds, including a rare group of lipid mediators called resolvins and furan fatty acids.
Green lipped mussel extract is best known for its ability to support joint health and reduce inflammation, especially in conditions such as osteoarthritis, rheumatoid arthritis, and general joint stiffness or pain. Its compounds help protect cartilage, support synovial fluid, and modulate inflammatory pathways, often offering benefits similar to NSAIDs but with fewer gastrointestinal side effects.
In addition to musculoskeletal support, green lipped mussel may promote skin health, cardiovascular function, and respiratory health, particularly by modulating immune response and reducing systemic inflammation. It is commonly available in capsule, powder, oil, or freeze-dried forms, and is frequently included in both human and veterinary joint support supplements.
Historical Use
Although the use of green lipped mussel as a standardized supplement is a modern development, the indigenous Māori people of New Zealand have long consumed these mussels as part of their traditional coastal diet. Researchers in the 20th century noted that coastal Māori communities had remarkably low rates of arthritis and joint disease, prompting scientific investigation into the mussels’ potential anti-inflammatory benefits.
In the 1970s, green lipped mussel was first studied as a nutraceutical, and early trials confirmed its potential in reducing joint pain and improving mobility, particularly in aging populations. Since then, it has become a well-established natural remedy for joint disorders and inflammation-related conditions, often compared favorably to glucosamine and chondroitin sulfate.
Today, green lipped mussel extract remains a clinically supported, naturally sourced alternative for people seeking relief from joint pain, stiffness, and inflammation, as well as a sustainable marine-based omega-3 source with applications across orthopedic, dermatologic, and respiratory wellness.
Green-lipped mussel is used for these health conditions
Arthritis (Scientific)
Asthma (Scientific)
Autoimmune Disorders (Scientific)
Cartilage Damage (Scientific)
Inflammation (Scientific)
Rheumatoid Arthritis (Scientific)
green-lipped mussel is used to support these body systems
Immune System (Scientific)
Joints (Scientific)
Skeletal System (Bones) (Scientific)
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