Hydroxymatairesinol
Other names for hydroxymatairesinol
7-hydroxymatairesinol
7-hydroxymatairesinol (hmr) potassium acetate complex
hmr lignan-7-hydroxymatairesinol
hydroxymatairesinol
hydroxymatairesinol [hmr] lignans
hydroxymatairesinol potassium acetate
hydroxymatairesinol potassium acetate complex
patented extract of 7-hydroxymatairesinol hmrlignan
Synopsis of hydroxymatairesinol
History
Hydroxymatairesinol is a naturally occurring lignan, primarily found in the heartwood of the Norway spruce (Picea abies). Its historical use can be traced to traditional medicinal practices in Northern Europe, where extracts of spruce and related species were employed as remedies for a variety of health concerns. These included treatments for inflammation, infections, and as a general tonic to support overall wellbeing. In folk medicine, the inner bark and wood of spruce trees were often brewed into teas or used in poultices, harnessing the plant’s bioactive compounds to promote healing and resilience.
Recent scientific exploration has validated many of these traditional applications, revealing that hydroxymatairesinol exhibits potent antioxidant and phytoestrogenic properties. This lignan has been particularly valued for its ability to modulate hormonal balance, support cardiovascular health, and enhance immune response. Its antioxidant activity helps combat oxidative stress, which is linked to aging and chronic diseases, thus underscoring its role as a valuable component in modern nutritional products.
In herbal combinations, hydroxymatairesinol is frequently paired with other lignan-rich botanicals such as flaxseed, sesame, and certain berries. These synergistic blends amplify the health benefits, delivering a broader spectrum of phytonutrients that support hormone metabolism, cardiovascular function, and antioxidant defenses. The inclusion of hydroxymatairesinol in such formulas exemplifies the integration of traditional wisdom and contemporary science, offering safe, natural, and effective solutions for promoting long-term health and vitality.
Traditional and scientific validation
Hydroxymatairesinol is a naturally occurring lignan found predominantly in the heartwood of the Norway spruce (Picea abies). Its discovery has sparked interest due to its structural similarity to other plant lignans that exhibit phytoestrogenic properties, potentially impacting human health through antioxidant, anti-inflammatory, and hormone-modulating activities. Historically, lignans have been consumed as part of a plant-rich diet and have been associated with reduced risk of certain chronic diseases, such as cardiovascular disease and hormone-related cancers.
Scientific interest in hydroxymatairesinol centers on its possible health benefits when included in nutritional supplements. Several in vitro and animal studies have suggested that it may exert antioxidant effects, support healthy lipid metabolism, and modulate immune response. Notably, some research indicates that hydroxymatairesinol can be metabolized by gut bacteria into enterolignans, compounds that may contribute to maintaining hormonal balance.
While preliminary data are promising, clinical studies in humans remain limited. A few small-scale trials have explored its safety and bioavailability, showing favorable tolerance and metabolic conversion. However, conclusive evidence regarding its efficacy for specific health outcomes is lacking, and more rigorous, large-scale human trials are needed to validate its benefits and mechanisms of action.
In summary, hydroxymatairesinol represents a promising ingredient in nutritional products due to its biological activities and potential health-promoting effects. Ongoing research will be essential to fully understand its contributions and to substantiate its role in supporting human health.
Hydroxymatairesinol is used for these health conditions
Cancer (prevention) (Scientific)
Inflammation (Scientific)
hydroxymatairesinol is used to support these body systems
Estrogen (Scientific)
