Triple Magnesium Complex | Heart, Brain & Kidney Support

A triple Magnesium Complex brings together multiple highly bioavailable forms of Magnesium in a single supplement, making it easier to keep up with one of the most important — and most commonly under-consumed — minerals in the human body. Magnesium is the fourth most abundant cation in the body and serves as a cofactor in more than 300 enzyme systems that regulate everything from energy production and nerve signaling to blood pressure and heart rhythm.

Despite its critical roles, research confirms that an estimated 56–68% of Americans do not obtain enough Magnesium from their daily diet to meet the Recommended Dietary Allowance. That shortfall is linked to a wide range of health concerns — from muscle cramps and fatigue to cardiovascular irregularities and impaired nervous system function.

Nature's Sunshine Magnesium Complex addresses this gap by combining Magnesium citrate and Magnesium malate — two organic forms prized for their solubility and absorption. Two capsules provide 184 mg of Magnesium in a highly soluble formula designed to support the heart, brain, and kidneys.

Not all Magnesium supplements are created equal. Magnesium is available in organic forms (citrate, malate, glycinate, lactate) and inorganic forms (oxide, sulfate, chloride). The distinction matters because organic forms are generally more soluble and better absorbed.

Magnesium citrate, one of the two forms in this triple Magnesium Complex, is among the most bioavailable options available. Research shows that Magnesium citrate has high solubility even in water (55%) and is substantially more soluble than Magnesium oxide in all states of acid secretion. That high solubility translates to more efficient absorption in the digestive tract.

Magnesium malate — Magnesium bound to malic acid — is another well-regarded organic form. Like citrate, it falls into the category of organic Magnesium salts that are generally more soluble and have higher bioavailability than their inorganic counterparts.

By combining these two forms, Magnesium Complex offers what we consider a well-rounded approach to supplementation — highly soluble Magnesium that's designed for optimum effectiveness. If you have questions about which form of Magnesium may be right for your individual needs, our naturopath is available for a free consultation.

Because Magnesium plays such a broad role in the body — from cardiac rhythm and blood vessel tone to nerve signaling and kidney mineral balance — many different people may benefit from a triple Magnesium Complex. This formula is specifically formulated to support the cardiovascular system and help brain, kidney, and heart functions.

Adults concerned about heart health. Research suggests that higher dietary and circulating Magnesium levels are inversely associated with risks of coronary heart disease, stroke, and total cardiovascular disease. In 2022, the FDA approved a qualified health claim stating that consuming diets with adequate Magnesium may reduce the risk of high blood pressure, though the agency noted the evidence is inconsistent and inconclusive.

Those seeking kidney support. Magnesium is a well-established inhibitor of calcium oxalate crystallization in urine. The kidneys are the primary regulators of whole-body Magnesium homeostasis, and higher urinary Magnesium from adequate intake is associated with reduced risk of kidney stone formation.

People focused on nervous system wellness. Magnesium is fundamental to nervous system function, modulating neuronal excitability and neuromuscular transmission. Deficiency is associated with symptoms ranging from muscle cramps and tingling to mood changes.

Older adults. As we age, Magnesium absorption and retention can decrease. Older adults are more susceptible to deficiency due to decreased absorption from food, increased medication use (certain diuretics can deplete Magnesium), and potential dietary restrictions.

People on certain medications. Loop and thiazide diuretics, proton pump inhibitors (PPIs), and certain antibiotics can all affect Magnesium status. If you take any of these medications, talking with a healthcare professional about your Magnesium levels may be worthwhile.

Take 2 capsules twice daily with a meal.

Each serving of 2 capsules provides 184 mg of Magnesium from Magnesium citrate and Magnesium malate. The product comes in a 100-capsule bottle.

The Recommended Dietary Allowance (RDA) for Magnesium is 400–420 mg/day for adult men and 310–320 mg/day for adult women. During pregnancy, the requirement increases to about 350–360 mg daily. The Tolerable Upper Intake Level (UL) for supplemental Magnesium is 350 mg — note that this applies only to Magnesium from supplements and medications, not from food.

Magnesium supplements can sometimes cause digestive effects such as softened stool, nausea, or cramping, particularly at higher doses. These side effects are more common with inorganic forms like Magnesium oxide; the organic forms in this product (citrate and malate) are generally better tolerated.

Important interactions to be aware of: Magnesium may interfere with the absorption of bisphosphonates, tetracycline and quinolone antibiotics, and gabapentin. If you take any of these medications, separate your Magnesium supplement by at least 2 hours (or 4–6 hours for certain antibiotics). If you are on diuretics or proton pump inhibitors, be aware that these medications can affect your Magnesium levels. Always consult your healthcare provider before starting a new supplement, especially if you take prescription medications.