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Top Nurex Magnesium Complex Ultra | Dual-Form Mg

Discover top nurex Magnesium Complex ultra with Magnesium citrate and malate for heart health, nervous system support, and bone density. 100 capsules, highly soluble.

Overview

Top Nurex Magnesium Complex Ultra: Dual-Form Magnesium for Heart, Brain & Bones

Magnesium is the fourth most abundant cation in the human body and a critical cofactor in more than 300 enzyme systems that regulate everything from energy production and muscle function to blood pressure and bone formation. Yet emerging evidence confirms that nearly two-thirds of the Western population falls short of the recommended daily allowance β€” a widespread gap that may contribute to cardiovascular, neurological, and skeletal concerns.

The top nurex Magnesium Complex ultra β€” Nature's Sunshine Magnesium Complex (Stock #1859-8) β€” addresses this gap by combining two highly soluble organic forms of Magnesium: Magnesium citrate and Magnesium malate. Organic Magnesium salts like citrate and malate are chelated to organic acid molecules, giving them generally higher solubility and bioavailability compared to inorganic forms such as Magnesium oxide. In fact, research shows Magnesium citrate has high solubility even in water (55%) and is substantially more soluble than Magnesium oxide in all states of acid secretion.

Each two-capsule serving delivers 184 mg of Magnesium, formulated to support the cardiovascular system, brain and kidney functions, and bone health. The 100-capsule bottle is designed for daily use, and if you have questions about whether this formula is right for your situation, our naturopath is available for a free consultation.

How It Works

Why Two Forms of Magnesium Matter

Not all Magnesium supplements are created equal. The form of Magnesium determines how well it dissolves and how efficiently your body can absorb it. This top nurex Magnesium Complex ultra pairs two complementary organic forms for optimum effectiveness.

Magnesium Citrate

Magnesium citrate is one of the most bioavailable supplemental forms available. Studies show it achieves 55% solubility in water alone and remains substantially more soluble than inorganic alternatives across varying levels of stomach acid. This high solubility translates to efficient absorption in the gastrointestinal tract.

Magnesium Malate

Magnesium malate is another organic form in which Magnesium is chelated to malic acid. Like citrate, organic Magnesium salts such as malate are generally more soluble and have higher bioavailability than inorganic counterparts. By combining two organic forms, this formula helps ensure your body has the best opportunity to absorb and utilize the Magnesium it needs.

Once absorbed, the Mg²⁺ ion serves as an indispensable cofactor across the body β€” from ATP synthesis and ion transport to bone metabolism, neuronal signaling, and inflammatory modulation.

What's inside

Key Ingredients

Magnesium citrate β€” 184 mg
Magnesium citrate is one of the most bioavailable supplemental forms of Magnesium, with high solubility even in water (55%) and substantially greater solubility than Magnesium oxide across all states of acid secretion. As a cofactor in over 300 enzyme systems, the Mg²⁺ ion it delivers supports a wide range of body systems. Research suggests Magnesium plays a well-documented role in cardiovascular health: higher dietary and circulating Magnesium levels are inversely associated with risks of coronary heart disease, stroke, and total cardiovascular disease, and supplementation may produce modest but significant reductions in blood pressure β€” particularly in Magnesium-deficient or hypertensive individuals β€” through mechanisms including vasodilation and calcium channel antagonism. Magnesium is also a well-established cofactor in cardiac electrophysiology, modulating ion channel exchanges and action potentials; hypomagnesemia is strongly linked to both ventricular and supraventricular arrhythmias. For arterial health, a 24-week RCT found that 350 mg/day Magnesium citrate significantly reduced arterial stiffness as measured by pulse wave velocity. In the skeletal system, Magnesium is an essential cofactor in bone mineral metabolism and enzyme activity for bone matrix synthesis, and it is required for vitamin D activation and calcium metabolism. Observational data from large cohort studies found higher Magnesium intake associated with 2–3% greater bone density in women, and the COMB clinical trial showed supplementation may attenuate bone loss. Magnesium is the second most abundant mineral in bone, and low levels are associated with increased osteoporosis risk through promoted osteoclast activity and disrupted calcium homeostasis. For the nervous system, Magnesium acts as a natural NMDA receptor antagonist, modulating synaptic transmission and neuronal excitability; deficiency is associated with increased risk of neurological symptoms including neuromuscular hyperexcitability, tremors, and conditions ranging from migraine to depression. A 2017 RCT showed 248 mg/day Magnesium significantly reduced both depression and anxiety scores, supporting its role in inhibitory-excitatory neurotransmitter balance. Additionally, research suggests Magnesium may support nerve health by blocking NMDA receptors and regulating calcium and potassium channels, with clinical evidence supporting its role in nerve excitability modulation and neuropathic discomfort reduction. A meta-analysis of 17 RCTs found Magnesium supplementation significantly decreased serum C-reactive protein and increased nitric oxide levels, suggesting anti-inflammatory properties.
Magnesium malate β€” 184 mg
Magnesium malate is an organic form of Magnesium in which the mineral is chelated to malic acid. Organic Magnesium salts such as malate are generally more soluble and have higher bioavailability than inorganic forms like Magnesium oxide, supporting efficient absorption. Like Magnesium citrate, the Mg²⁺ delivered by Magnesium malate serves as a cofactor in more than 300 enzymatic reactions encompassing protein synthesis, muscle and nerve function, blood glucose control, and blood pressure regulation. It plays a pivotal role in ATP synthesis β€” indispensable for cellular energy generation across virtually all tissues β€” and is an essential cofactor for the Na,K-ATPase ion pump. Research suggests Magnesium supports the cardiovascular system by regulating cardiac excitation, vascular tone, and endothelial function; lower levels are consistently associated with higher risks of arrhythmia, hypertension, coronary artery disease, and heart failure. For the musculoskeletal system, Magnesium governs calcium flux in muscle and bone cells and modulates parathyroid hormone activity; a systematic review and meta-analysis found that higher Magnesium intake is associated with increased hip and femoral neck bone mineral density in older adults, and clinical evidence shows supplementation may reduce muscle soreness and support muscle mass preservation. EFSA has recognized sufficient evidence that dietary Magnesium contributes to the maintenance of bones and teeth. In the nervous system, Magnesium is fundamental as a physiological NMDA receptor antagonist and regulator of neuromuscular transmission and nerve signaling. Research also suggests it may support individuals with restless leg syndrome: a randomized controlled trial found Magnesium significantly improved RLS symptom scores and sleep quality compared to placebo. Magnesium supplementation has also been associated with reduced muscle inflexibility and discomfort in sciatica patients, acting as an NMDA receptor antagonist blocking central sensitization relevant to chronic pain.
Magnesium Complex
Magnesium Complex
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Magnesium Complex
Magnesium Complex
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Who Benefits

Who May Benefit from This Magnesium Complex

Given that an estimated 56–68% of Americans do not obtain enough Magnesium daily to meet the recommended dietary allowance, a broad range of adults may benefit from supplementation. The top nurex Magnesium Complex ultra may be especially relevant for:

  • Adults concerned about heart health β€” Research suggests higher Magnesium levels are inversely associated with risks of coronary heart disease, stroke, and total cardiovascular disease. The FDA approved a qualified health claim in 2022 noting that adequate Magnesium may reduce the risk of hypertension, though it characterizes the evidence as inconsistent and inconclusive.
  • Those supporting bone density β€” Magnesium is involved in bone formation, influences osteoblast and osteoclast activity, and is required for vitamin D activation. People with higher Magnesium levels may have higher bone mineral density.
  • Individuals seeking nervous system support β€” Magnesium modulates neuronal excitability through NMDA receptor blockade and voltage-gated calcium antagonism, supporting normal nerve function.
  • Older adults β€” As we age, Magnesium absorption and retention can decrease, and older adults are more susceptible to deficiency due to decreased dietary absorption, increased medication use (such as diuretics), and potential dietary restrictions.
  • People taking certain medications β€” Loop and thiazide diuretics, proton pump inhibitors, and other medications can deplete Magnesium stores over time.

If you're unsure whether Magnesium supplementation fits your health goals, our naturopath is happy to help β€” free of charge.

Directions

How to Take Magnesium Complex

Take 2 capsules twice daily with a meal.

Each bottle contains 100 capsules. Taking this supplement with food supports absorption and may help minimize occasional stomach-related side effects, which are the most common issues associated with Magnesium supplements. These side effects β€” such as softening of stool, nausea, or cramping β€” tend to occur at higher doses and are more common with inorganic forms of Magnesium. The organic citrate and malate forms in this complex are designed for high solubility and gentle absorption.

Important safety note: Magnesium supplements may interact with certain medications. If you take bisphosphonates (such as alendronate), separate intake by at least 2 hours. If you take tetracycline or quinolone antibiotics, the antibiotic should be taken at least 2 hours before or 4–6 hours after Magnesium. Magnesium may also reduce the absorption of gabapentin. Always consult your healthcare provider if you are on medication or have impaired kidney function.

About the author

Written by Greg Howlett

GH

Greg Howlett

Founder

Greg has spent over a decade helping customers choose the right natural-health products. He personally vets every formula we carry and writes these guides to cut through the marketing noise with practical, experience-based advice.

FAQ

Frequently asked questions

What forms of Magnesium are in this supplement?

This Magnesium Complex contains two organic forms: Magnesium citrate and Magnesium malate. Organic forms of Magnesium are generally more soluble and have higher bioavailability than inorganic alternatives. Magnesium citrate, in particular, has been shown to achieve 55% solubility in water and is substantially more soluble than Magnesium oxide across varying levels of stomach acid.

How much Magnesium does each serving provide?

Two capsules of Magnesium Complex provide 184 mg of Magnesium. The recommended usage is 2 capsules twice daily with a meal, for a total daily serving of 4 capsules. The Recommended Dietary Allowance (RDA) for Magnesium is 400–420 mg/day for adult men and 310–320 mg/day for adult women.

How does this Magnesium Complex support heart health?

Research suggests that higher dietary and circulating Magnesium levels are inversely associated with risks of coronary heart disease, stroke, and total cardiovascular disease. Magnesium regulates cardiac ion channels, myocardial conduction, vascular tone, and endothelial function. Multiple meta-analyses and RCTs show supplementation may produce modest but significant blood pressure reductions, particularly in Magnesium-deficient or hypertensive individuals. In 2022, the FDA approved a qualified health claim stating that consuming diets with adequate Magnesium may reduce the risk of hypertension, though the FDA characterizes the evidence as inconsistent and inconclusive.

Can Magnesium supplements cause side effects?

The most common side effects of Magnesium supplements are stomach-related issues such as softening of stool, nausea, and cramping. These side effects tend to occur at higher doses and are more common with inorganic forms like Magnesium oxide. The organic citrate and malate forms used in this complex are designed for high solubility and are generally gentler on the digestive system. Hypermagnesemia from supplements is rare in individuals with normal kidney function, as the kidneys efficiently excrete excess Magnesium.

Who is most at risk for Magnesium deficiency?

An estimated 56–68% of Americans do not consume enough Magnesium to meet the RDA. Groups particularly at risk include older adults (due to decreased absorption), individuals with gastrointestinal disorders, those with type 2 diabetes, people with alcohol dependence, and individuals taking certain long-term medications such as loop or thiazide diuretics and proton pump inhibitors.

Does Magnesium interact with medications?

Yes, Magnesium can interact with several medications. It may decrease the absorption of bisphosphonates (separate by at least 2 hours), form insoluble complexes with tetracycline and quinolone antibiotics (take the antibiotic at least 2 hours before or 4–6 hours after Magnesium), and reduce the absorption of gabapentin by about 20%. Loop and thiazide diuretics can deplete Magnesium, while prolonged use of proton pump inhibitors can cause hypomagnesemia. Consult your healthcare provider before combining Magnesium with any medication.

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