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Nature’s Way Chlorofresh Chlorophyll Liquid Guide

Explore Nature's Way Chlorofresh Chlorophyll Liquid β€” what it is, key ingredients, how it supports blood cleansing, immune health, and natural deodorizing.

Overview

What Is Nature's Way Chlorofresh Chlorophyll Liquid?

Nature's Way Chlorofresh Chlorophyll Liquid is a 32-ounce Liquid Chlorophyll formula designed to support natural blood-cleansing processes, encourage proper immune response, strengthen the body on a cellular and molecular level, and act as a natural deodorizer. It harnesses sodium copper chlorophyllin β€” a water-soluble derivative of the green pigment that powers photosynthesis in plants β€” along with spearmint aerial parts oil.

Chlorophyll has nourished plant life for millennia by converting sunlight into energy. But Chlorophyll and its derivatives have also been part of the human diet throughout history as an integral component of vegetable foodstuffs, and Chlorophyll derivatives have a long history in traditional medicine dating back to at least the mid-twentieth century, including uses for wound healing, as an anti-inflammatory agent, and as an internal deodorant.

If you have questions about whether nature's way chlorofresh Chlorophyll liquid fits into your wellness routine, our naturopath is available for a free consultation β€” no appointment fees, no membership required.

How It Works

The Science and Tradition Behind Liquid Chlorophyll

The active form in this formula β€” sodium copper chlorophyllin β€” is a semisynthetic derivative of natural Chlorophyll. In natural Chlorophyll, a magnesium atom sits at the center of a porphyrin ring with a fat-soluble phytol tail. In chlorophyllin, the magnesium is replaced by copper and the phytol tail is removed, making the compound water-soluble and suitable for liquid supplementation.

Chlorophyllin's biological activities are linked to the chemical nature of its porphyrin ring, which allows it to function as a hydrogen donor, stopping chain oxidation processes. Research suggests chlorophyllin presents significant antioxidant activity through chelation of reactive ions and scavenging of free radicals, helping to prevent oxidative DNA damage and lipid peroxidation.

Chlorophyll and sodium copper chlorophyllin are also able to form tight molecular complexes with certain chemicals known or suspected to cause cancer, including polyaromatic hydrocarbons found in tobacco smoke and aflatoxin B1. This binding may interfere with gastrointestinal absorption, reducing the amount that reaches susceptible tissues. Additionally, chlorophyllin has been documented to induce phase 2 cytoprotective genes in mammalian systems, a complementary detoxification pathway.

Historically, Chlorophyll has been marketed as an "internal deodorant" since the 1950s. One study published in 1980 found that administration of chlorophyllin was "helpful in controlling body and fecal odors" in 62 geriatric nursing home patients. A separate study in Japanese patients with trimethylaminuria found that oral chlorophyllin significantly decreased urinary trimethylamine.

What's inside

Key Ingredients

Sodium Copper Chlorophyllin β€” 90 mg
Sodium copper chlorophyllin (SCC) is a water-soluble derivative of Chlorophyll in which the central magnesium atom is replaced by copper and the fat-soluble phytol tail is removed. This structural modification makes it suitable for liquid supplementation while preserving the bioactive porphyrin ring. SCC contains two related copper-containing compounds β€” trisodium copper chlorin e6 and disodium copper chlorin e4. Its benefits span multiple body systems, supported by varying levels of evidence. <strong>Blood health:</strong> Chlorophyll's structural similarity to hemoglobin β€” both are tetrapyrrole ring structures β€” has traditionally led practitioners to associate Chlorophyll-rich preparations with supporting red blood cell production. Research on sodium iron chlorophyllin (a related derivative) has shown clinical evidence supporting blood health: a Phase IV multicenter randomized controlled trial across 31 hospitals found significant hemoglobin increases in adults and children, and a 2022 meta-analysis of 39 trials further supports efficacy for iron-deficiency anemia. However, standard plant Chlorophyll containing magnesium (rather than iron) lacks robust human clinical evidence for directly raising hemoglobin or red blood cell counts. <strong>Immune system support:</strong> Chlorophyllin has traditionally been attributed immune-supporting properties based on preclinical evidence showing immunostimulatory effects, potential enhancement of white blood cell production, and anti-inflammatory modulation. Traditional and naturopathic frameworks position Chlorophyll as an immune tonic, though direct human clinical evidence for immune-specific outcomes such as infection resistance or immune cell counts is currently absent. <strong>Whole body cleanse:</strong> Chlorophyll has been used as a traditional internal cleanser and detoxifier for decades, based on its documented ability to bind carcinogens and reduce their systemic bioavailability, support liver detoxification enzyme systems, and reduce gut-derived toxin absorption. While aflatoxin chemoprevention data provide a scientific basis for specific toxin binding, the broader concept of a whole body cleanse via Chlorophyll is rooted in traditional use and naturopathic practice. <strong>Liver detox:</strong> Research suggests Chlorophyll and its derivatives bind lipophilic carcinogens and aflatoxins in the gastrointestinal tract, reducing their absorption and hepatic exposure. A well-designed crossover clinical trial in Qidong, China found chlorophyllin supplementation significantly reduced aflatoxin-DNA adduct biomarkers in humans, providing direct evidence of liver carcinogen reduction. <strong>Environmental toxin protection:</strong> A landmark randomized, double-blind, placebo-controlled trial in 180 adults in Qidong, China found that 100 mg chlorophyllin three times daily for 4 months produced a 55% reduction in urinary aflatoxin-DNA adduct biomarkers versus placebo. A subsequent Phase 0 human pharmacokinetic study confirmed Chlorophyll and chlorophyllin reduce aflatoxin bioavailability. <strong>Natural deodorizer:</strong> SCC has been used orally as an internal deodorant for more than 50 years without any serious side effects, though the evidence in healthy individuals is largely drawn from small, dated studies.
Spearmint Aerial Parts Oil
Spearmint (Mentha spicata) is an aromatic herb in the Lamiaceae family, native to Europe and southern temperate Asia, and has been valued for centuries across multiple cultures β€” from ancient Roman baths to traditional Iranian medicine β€” for its pleasant aroma and wide-ranging traditional uses. The essential oil is characterized by high concentrations of carvone (22–73%) and limonene (8–31%), along with other constituents including piperitone, menthol, myrcene, beta-pinene, linalool, and caryophyllene. Its non-volatile fraction is rich in rosmarinic acid and flavonoids. <strong>Immune system:</strong> Research suggests spearmint's rosmarinic acid and flavonoids may modulate immune function through antioxidant, anti-inflammatory, antibacterial, and immunosuppressant mechanisms documented in preclinical studies. Rosmarinic acid has demonstrated immunosuppressant activity, including inducing apoptosis of activated T cells in preclinical models. In this formula, spearmint aerial parts oil complements the chlorophyllin by contributing its own traditional history of use for digestive comfort, breath freshening, and overall well-being.
Liquid Chlorophyll
Liquid Chlorophyll
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Liquid Chlorophyll
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Ideal Users

Who May Benefit from Nature's Way Chlorofresh Chlorophyll Liquid

Nature's way chlorofresh Chlorophyll liquid may appeal to individuals interested in supporting their body's natural blood-cleansing processes or encouraging a healthy immune response. It has also traditionally been used by those looking for a natural internal deodorizer β€” a use that dates back to the 1950s.

People interested in whole-body cleansing through traditional naturopathic approaches may find chlorophyllin aligns with their wellness goals. Chlorophyll has historically been used as an internal cleanser based on its ability to bind certain compounds in the gastrointestinal tract.

Because sodium copper chlorophyllin supplements have not been tested for safety in pregnant or lactating women, they should be avoided during pregnancy and lactation. Individuals with rare disorders of copper metabolism, such as Wilson's disease, should limit exposure to copper additives, including supplemental sodium copper chlorophyllin. If you take medications β€” particularly sedatives or medications that affect the liver β€” it's wise to speak with a healthcare professional before starting any new supplement.

Not sure if this formula is right for you? Our naturopath offers free consultations to help you sort through the details.

Usage Guide

How to Take Nature's Way Chlorofresh Chlorophyll Liquid

Take 2 tablespoons (30mL) in an 8 fl oz glass of cold water daily. Refrigerate after opening.

One note worth mentioning: when taken orally, supplemental chlorophyllin may cause green discoloration of urine or feces, or yellow or black discoloration of the tongue. There have also been occasional reports of diarrhea. These effects are not harmful but are worth being aware of. Additionally, oral chlorophyllin may result in false positive results on guaiac card tests for occult blood β€” something to mention to your healthcare provider if relevant.

About the author

Written by Greg Howlett

GH

Greg Howlett

Founder

Greg has spent over a decade helping customers choose the right natural-health products. He personally vets every formula we carry and writes these guides to cut through the marketing noise with practical, experience-based advice.

FAQ

Frequently asked questions

Is nature's way chlorofresh Chlorophyll liquid actual Chlorophyll or something different?

The active ingredient is sodium copper chlorophyllin, a semisynthetic, water-soluble derivative of Chlorophyll. In this form, the central magnesium atom of natural Chlorophyll is replaced by copper and the fat-soluble phytol tail is removed, making it dissolve cleanly in water. Most commercial Liquid Chlorophyll products use chlorophyllin rather than natural Chlorophyll for this reason.

Will Liquid Chlorophyll turn my urine or stool green?

It can. When taken orally, supplemental chlorophyllin may cause green discoloration of urine or feces, or yellow or black discoloration of the tongue. These are harmless cosmetic effects. It's also worth noting that oral chlorophyllin may result in false positive results on guaiac card tests for occult blood, so let your healthcare provider know if you're taking it.

Is nature's way chlorofresh Chlorophyll liquid safe to take long term?

Natural chlorophylls are not known to be toxic, and no toxic effects have been attributed to chlorophyllin despite more than 50 years of clinical use in humans. However, since safety has not been tested in pregnant or lactating women, it should be avoided during pregnancy and lactation. Individuals with Wilson's disease or other copper metabolism disorders should also avoid sodium copper chlorophyllin due to its copper content. If you take medications, consult a healthcare professional β€” our naturopath is available for free consultations if you'd like guidance.

How does chlorophyllin support blood health?

Chlorophyll's structural similarity to hemoglobin β€” both are tetrapyrrole ring structures β€” has historically led to the traditional belief that Chlorophyll-rich preparations support red blood cell production. Research on sodium iron chlorophyllin (a related derivative containing iron) has shown clinical evidence for blood health in iron-deficiency anemia studies. However, standard plant-based Chlorophyll supplements containing magnesium or copper (rather than iron) lack robust human clinical evidence for directly raising hemoglobin levels.

Does Chlorophyll actually work as an internal deodorizer?

Chlorophyllin has been used as an internal deodorant since the 1950s. One study published in 1980 found it "helpful in controlling body and fecal odors" in 62 geriatric nursing home patients, and a separate study found that oral chlorophyllin significantly decreased urinary trimethylamine in patients with trimethylaminuria. However, the evidence in healthy individuals is largely drawn from small, dated studies, so the benefit may be more relevant for specific populations than for general body odor.

Does Liquid Chlorophyll interact with any medications?

A case of delayed methotrexate clearance was reported following administration of a complementary medication containing Chlorophyll, suggesting a potential pharmacokinetic interaction with at least one chemotherapy agent. Chlorophyllin also forms tight molecular complexes with certain chemicals, and carefully controlled studies have not been undertaken to determine whether this mechanism might limit uptake of required nutrients or co-administered medications. If you take prescription medications, it's best to consult a healthcare professional before adding Chlorophyll supplementation.

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Nature's Way Chlorofresh Chlorophyll Liquid Guide