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Nature Made Magnesium Complex | Dual-Form Support

Explore Nature's Sunshine Magnesium Complex with citrate & malate forms. Supports heart health, nervous system, and muscle function. 184 mg per 2 capsules.

Essential Mineral

What Is Nature Made Magnesium Complex and Why Does It Matter?

Magnesium Complex from Nature's Sunshine delivers this essential mineral in two highly soluble organic forms β€” Magnesium citrate and Magnesium malate β€” to support your cardiovascular system, brain, heart, and kidneys. Two capsules provide 184 mg of Magnesium, and the product is designed for optimum effectiveness through the use of these well-absorbed forms.

Magnesium is the fourth most abundant cation in the human body and serves as a cofactor in more than 300 enzyme systems that regulate everything from energy production and muscle function to blood pressure and nerve signaling. Despite its critical importance, an estimated 56–68% of Americans do not obtain enough Magnesium from their daily diet to meet the recommended daily allowance.

That widespread shortfall is why a nature made Magnesium Complex built around bioavailable forms can be so valuable. Magnesium deficiency can manifest as muscle cramps, fatigue, weakness, and even cardiovascular abnormalities β€” symptoms that many people simply chalk up to aging or stress. Maintaining adequate Magnesium status, on the other hand, supports cardiometabolic resilience, skeletal strength, neurological stability, and healthy aging.

Why Two Forms

How Magnesium Citrate and Malate Work Together

Not all Magnesium supplements are created equal. Magnesium supplements are broadly categorized into organic and inorganic compounds. Organic forms β€” such as citrate, malate, and glycinate β€” are chelated to organic molecules, making them generally more soluble and more bioavailable than inorganic forms like Magnesium oxide.

This nature made Magnesium Complex pairs two organic forms for complementary benefits. Magnesium citrate is one of the most bioavailable forms available, with high solubility even in water (55%) and substantially greater solubility than Magnesium oxide across all states of acid secretion. Magnesium malate likewise belongs to the organic salt category, meaning it shares that favorable solubility and absorption profile.

By combining citrate and malate together in a single capsule, Magnesium Complex offers a highly soluble formula that the body can readily put to use. This is particularly important because Magnesium must be absorbed before it can participate in the hundreds of enzymatic reactions your body depends on β€” from ATP synthesis and muscle contraction to neurotransmitter balance and cardiac electrophysiology.

What's inside

Key Ingredients

Magnesium citrate β€” 184 mg
Magnesium citrate is one of the most bioavailable supplemental forms of Magnesium, with high solubility even in water (55%) and substantially greater solubility than Magnesium oxide. As a cofactor in over 300 enzymatic reactions, this form of Magnesium supports a wide range of body systems. Research suggests it plays a well-documented role in cardiovascular health: large meta-analyses and prospective cohort studies consistently associate higher Magnesium levels with lower risks of coronary heart disease, atrial fibrillation, and heart failure. Multiple RCTs and meta-analyses show it may modestly but significantly reduce blood pressure, particularly in Magnesium-deficient or hypertensive individuals, through mechanisms including vasodilation, calcium channel antagonism, and RAAS modulation. A 24-week RCT using 350 mg/day Magnesium citrate significantly reduced arterial stiffness as measured by pulse wave velocity. Magnesium is also fundamental to nervous system function, acting as a physiological NMDA receptor antagonist that modulates synaptic transmission and neuronal excitability; hypomagnesemia is clinically associated with neuromuscular hyperexcitability, tremors, and neurological disorders ranging from migraine to depression. For muscles, Magnesium is essential for ATP synthesis, muscle contraction, and electrolyte homeostasis β€” deficiency is associated with muscle cramps, weakness, and impaired performance. A 2024 systematic review found Magnesium supplementation reduced muscle soreness, improved performance and recovery, and exerted a protective effect on muscle damage in physically active individuals. Research also suggests Magnesium plays a critical role in nerve excitability by blocking NMDA receptors and regulating calcium and potassium channels, with clinical evidence supporting its use for nerve excitability modulation and neuropathic pain reduction. Additionally, Magnesium is a cofactor in dopamine synthesis and a blocker of NMDA glutamate receptor channels, supporting inhibitory-excitatory neurotransmitter balance.
Magnesium malate β€” 184 mg
Magnesium malate is an organic form of Magnesium chelated to malic acid, offering favorable solubility and bioavailability compared to inorganic Magnesium salts. Like Magnesium citrate, it serves as a cofactor for over 300 enzymatic reactions and supports the same broad range of body systems. Research suggests Magnesium malate contributes to cardiovascular health by regulating cardiac excitation, vascular tone, and endothelial function β€” lower Magnesium levels are consistently associated with higher risks of arrhythmia, hypertension, coronary artery disease, and heart failure. Magnesium is a well-established cofactor in cardiac electrophysiology, modulating ion channel exchanges and action potentials; a meta-analysis of 22 studies found significant reductions in both ventricular and supraventricular arrhythmias with Magnesium supplementation. For the musculoskeletal system, Magnesium malate supports muscle contraction and relaxation through its role in ATP synthesis and intracellular calcium transport. Studies suggest Magnesium deficiency impairs muscle relaxation β€” muscles contract normally but may struggle to fully release when levels are low. Magnesium malate also supports nervous system function by acting as a natural NMDA receptor antagonist and regulating neuronal excitability and neuromuscular transmission. Clinical evidence further suggests Magnesium supplementation may support nerve health, with benefits observed for nerve excitability modulation and neuropathic pain reduction, particularly in individuals with existing deficiency. Research also indicates Magnesium supplementation significantly decreases serum C-reactive protein (CRP) and increases nitric oxide (NO) levels, according to a 2022 meta-analysis of 17 RCTs, suggesting a role in supporting a healthy inflammatory response.
Magnesium Complex
Magnesium Complex
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Magnesium Complex
Magnesium Complex
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Who Benefits

Who Should Consider Magnesium Complex?

Because Magnesium is involved in so many fundamental body processes, a wide range of people may benefit from this nature made Magnesium Complex. If you experience occasional muscle cramps or tension, Magnesium's role in muscle contraction and relaxation β€” specifically its involvement in ATP synthesis and intracellular calcium transport β€” makes it a mineral worth paying attention to.

Adults concerned about cardiovascular wellness may also find this formula relevant. Research suggests higher dietary and circulating Magnesium levels are inversely associated with risks of coronary heart disease, stroke, and total cardiovascular disease. Magnesium also modulates cardiac ion channels, myocardial conduction, and heart rhythm.

Certain groups face a higher risk of Magnesium inadequacy. These include older adults (due to decreased absorption from food and increased medication use), individuals with gastrointestinal disorders, those with type 2 diabetes, and people taking long-term medications such as diuretics or proton pump inhibitors, which can deplete Magnesium. Men older than 70 and teenage girls are identified as most likely to have low Magnesium intakes.

If you're unsure whether Magnesium supplementation is right for your individual needs, our naturopath is available for a free consultation to help you explore your options.

Usage Guide

How to Take Magnesium Complex

Take 2 capsules twice daily with a meal. Each bottle contains 100 capsules. Taking Magnesium with food supports absorption and may reduce the chance of mild stomach-related side effects.

It is worth noting that Magnesium supplements can interact with certain medications. Magnesium may decrease the absorption of oral bisphosphonates (used for osteoporosis) and should be separated from them by at least 2 hours. It can also form insoluble complexes with tetracycline and quinolone antibiotics β€” those antibiotics should be taken at least 2 hours before or 4–6 hours after Magnesium. Loop and thiazide diuretics may deplete Magnesium through increased urinary excretion, while proton pump inhibitors taken for prolonged periods can cause low Magnesium levels. Magnesium may also reduce the absorption of gabapentin by approximately 20%.

If you take any prescription medications, we recommend speaking with your healthcare provider or reaching out to our naturopath for a free consultation before starting supplementation.

Deficiency Matters

Understanding Magnesium Deficiency

Early signs and symptoms of Magnesium deficiency include loss of appetite, nausea, fatigue, and weakness. As deficiency worsens, numbness, tingling, muscle contractions and cramps, personality changes, abnormal heart rhythms, and coronary spasms can occur. Severe deficiency can disrupt mineral homeostasis and cause low serum calcium or potassium levels.

The diets of most people in the United States provide less than the recommended amounts of Magnesium. The RDA for adult men is 400–420 mg/day, while for adult women it is 310–320 mg/day. As we age, Magnesium absorption and retention can decrease, making supplementation even more relevant for older adults.

Emerging evidence confirms that nearly two-thirds of the population in the western world is not achieving the recommended daily allowance for Magnesium β€” a deficiency problem that research associates with conditions including hypertension, type 2 diabetes, osteoporosis, migraines, depression, and chronic inflammation.

About the author

Written by Greg Howlett

GH

Greg Howlett

Founder

Greg has spent over a decade helping customers choose the right natural-health products. He personally vets every formula we carry and writes these guides to cut through the marketing noise with practical, experience-based advice.

FAQ

Frequently asked questions

What forms of Magnesium are in Magnesium Complex?

Magnesium Complex contains two organic forms of Magnesium: Magnesium citrate and Magnesium malate. Both are highly soluble forms. Magnesium citrate, for example, has high solubility even in water (55%) and is substantially more soluble than inorganic forms like Magnesium oxide. Two capsules provide 184 mg of Magnesium.

How does this nature made Magnesium Complex support heart health?

Magnesium plays a well-documented role in cardiovascular health. Research suggests higher Magnesium levels are inversely associated with risks of coronary heart disease, stroke, and total cardiovascular disease. Magnesium is also a cofactor in cardiac electrophysiology, modulating ion channel exchanges and action potentials. Multiple RCTs and meta-analyses suggest it may modestly but significantly support healthy blood pressure levels, particularly in Magnesium-deficient individuals.

Can Magnesium help with muscle cramps?

Magnesium is the most studied mineral supplement for skeletal muscle cramps. It plays an essential role in muscle contraction and relaxation β€” deficiency impairs muscle relaxation, meaning muscles may contract normally but struggle to fully release when levels are low. A 2024 systematic review also found Magnesium supplementation reduced muscle soreness and exerted a protective effect on muscle damage in physically active individuals. However, Cochrane reviews note that evidence for cramp prophylaxis in older adults with idiopathic cramps is mixed.

Are there any side effects or drug interactions to be aware of?

The most common side effects of Magnesium supplements are stomach-related issues such as nausea, cramping, and diarrhea, which usually occur at higher doses and are more common with inorganic forms. Magnesium may interact with certain medications, including bisphosphonates, tetracycline and quinolone antibiotics, diuretics, proton pump inhibitors, and gabapentin. If you take any medications, consult your healthcare provider before starting Magnesium supplementation.

How much Magnesium do most adults need daily?

The Recommended Dietary Allowance (RDA) for adult men is 400–420 mg/day, and for adult women it is 310–320 mg/day. Pregnancy requires about 350–360 mg daily. The Tolerable Upper Intake Level (UL) for Magnesium from supplements only is 350 mg, though the RDA includes Magnesium from all sources β€” food, beverages, and supplements combined. An estimated 56–68% of Americans do not meet their daily Magnesium needs through diet alone.

Who is most at risk for Magnesium deficiency?

Certain groups face a higher risk of Magnesium inadequacy: older adults (due to decreased absorption and increased medication use), individuals with gastrointestinal disorders, those with type 2 diabetes, people with alcohol dependence, and those on long-term medications like diuretics or proton pump inhibitors. Men older than 70 and teenage girls are also identified as most likely to have low Magnesium intakes.

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