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Lymphatic Drainage Supplements | Nature’s Sunshine

Explore how Lymphatic Drainage supplements with Cleavers, Red clover, Stillingia & Prickly ash bark traditionally support lymphatic flow, fluid balance & well-being.

Overview

Lymphatic Drainage Supplements: Supporting Your Body's Natural Cleansing System

Your lymphatic system works quietly behind the scenes, carrying waste away from cells and helping maintain fluid balance throughout the body. When lymphatic flow becomes sluggish, it can affect how you feel day to day β€” from overall comfort to a sense of heaviness and puffiness.

Lymphatic Drainage supplements draw on centuries of herbal tradition to support the body's own waste-removal pathways. Nature's Sunshine Lymphatic Drainage is a liquid formula containing four time-honored botanicals β€” Cleavers aerial parts, Red clover blossom extract, Stillingia root, and Prickly ash bark β€” each with a long history of use by herbalists to encourage healthy lymph movement and fluid balance.

If you're exploring Lymphatic Drainage supplements for the first time and want personalized guidance, our naturopath is available for a free consultation to help you understand how these herbs may fit into your wellness routine.

How It Works

How These Herbs Traditionally Support Lymphatic Flow

Western herbalists have long grouped certain plants as "alteratives" β€” botanicals traditionally believed to promote the body's eliminative channels, particularly the lymphatic system and skin. Nature's Sunshine Lymphatic Drainage brings together four herbs from this tradition, each historically valued for a complementary role:

  • Cleavers has been a cornerstone lymphatic tonic in European, Native American, and Traditional Chinese Medicine for centuries, traditionally used to encourage lymph fluid movement and drain congested lymph nodes.
  • Red clover has longstanding use in Western herbalism as a "blood purifier" and alterative, traditionally recommended for swollen glands and chronic lymphatic congestion.
  • Stillingia root was cited by 19th-century Eclectic physicians as one of the most efficient vegetable alteratives, with King's American Dispensatory describing its action on the lymphatic system as unsurpassed.
  • Prickly ash bark is classified as a "lymphatic stimulant" in multiple professional herbal materia medica sources, traditionally noted for its stimulating effect upon the lymphatic system, circulation, and mucous membranes.

Together, these herbs form a formula that supports overall health and well-being and aids the circulatory system, according to Nature's Sunshine.

What's inside

Key ingredients

Cleavers aerial parts β€” 300 mg
Cleavers (Galium aparine) is perhaps the most recognized lymphatic tonic in Western herbal medicine. For centuries, herbalists across Europe, North America, and Asia have traditionally used this annual plant to encourage lymph fluid movement, drain congested lymph nodes, and support detoxification. It is also historically valued as a gentle, soothing diuretic β€” one of its best-attested traditional actions β€” traditionally used to promote healthy fluid balance, address water retention, and help reduce edema and dropsical swellings. Preclinical animal studies have confirmed increased urinary volume with Cleavers extracts, though human clinical trials are lacking. Phytochemical screening reveals that Cleavers is rich in iridoid glycosides, flavonoids, phenolic acids, tannins, and coumarins. Coumarins present in Galium species are noted in herbal texts to promote Lymphatic Drainage. Laboratory studies have demonstrated immunomodulatory activity: bioactive fractions containing polysaccharide, pectin, and polyphenolic complexes stimulated the activity of immunocompetent blood cells and increased lymphocyte proliferation in vitro. High concentrations of flavonoids, phenols, and tannins confirm substantial antioxidant capacity in laboratory assays. It is important to note that while Cleavers has a compelling ethnobotanical history and supportive phytochemical data, no clinical trials specifically evaluating lymphatic outcomes in humans have been published. Lymphatic tonic effects are supported by long-standing traditional use and indirect laboratory evidence.
Red clover blossom extract β€” 300 mg
Red clover (Trifolium pratense) has been one of the most recommended traditional lymphatic herbs in Western and naturopathic practice for centuries, used as a blood cleanser and lymphatic tonic. Part of a classification of herbs known as alteratives, Red clover has traditionally been recommended for swollen glands, chronic lymphatic congestion, and skin eruptions thought to arise from lymphatic stagnation. Its principal bioactive compounds are the isoflavones biochanin A, formononetin, genistein, and daidzein. Biochanin A has been shown to modulate NF-ΞΊB and MAPK signaling pathways relevant to vascular and lymphatic function. Red clover also contains natural coumarins β€” a class of benzopyrones that have been studied in numerous clinical trials for lymphedema. While modern research has focused primarily on Red clover's isoflavones for menopausal and cardiovascular benefits β€” a meta-analysis of eight randomized controlled trials confirmed isoflavone activity for menopausal symptoms β€” direct clinical evidence for lymphatic function remains traditional. Red clover's role in this formula is rooted in its longstanding herbal reputation as a lymphatic system supporter and blood purifier.
Stillingia root β€” 300 mg
Stillingia (Stillingia sylvatica), also known as Queen's Delight, is one of the most consistently cited traditional lymphatic herbs in North American folk and Eclectic medicine. The root was extensively used by 19th-century Eclectic physicians, who praised it as one of the most efficient vegetable alteratives β€” herbs believed to support the body's eliminative channels, particularly the lymphatic system and skin. King's American Dispensatory described its action on the lymphatic system as unsurpassed. It was historically employed for lymphatic gland enlargement, scrofulous conditions, and what practitioners termed "constitutional weakness" characterized by sluggish elimination. Eclectic physicians believed it increased the action of the skin, helped restore tone and free secretion, and supported the secretions of the kidneys and bowels. The root contains diterpene esters, tannins, resins, volatile oil, and an alkaloid called stillingine. It is important to note that no clinical studies exist to validate these traditional lymphatic uses. The herb's inclusion in this formula reflects its deep roots in North American herbal tradition rather than modern clinical evidence.
Prickly ash bark β€” 300 mg
Prickly ash (Zanthoxylum spp.) is classified as a "lymphatic stimulant" in multiple professional herbal materia medica sources. Naturopathic herbal texts note that "due to its stimulating effect upon the lymphatic system, circulation and mucous membranes it will have a role in the holistic treatment of many conditions." In North American herbalism, Prickly ash has deep roots in both Native American and early European settler medicine, traditionally valued for promoting peripheral circulation. People have historically taken Prickly ash for blood circulation problems and resulting conditions such as leg discomfort and cold extremities. The bark contains a rich array of phytochemicals including alkaloids such as chelerythrine and berberine, alkylamides (sanshools), coumarins, lignans, and flavonoids. Researchers have identified several types of coumarins and various alkaloids in Prickly ash that may help reduce platelet sticking. However, this is a traditional herbal classification without supporting human clinical evidence for lymphatic-specific outcomes. Its role in this formula is to traditionally complement the other lymphatic herbs by supporting healthy circulation.
Lymphatic Drainage
Lymphatic Drainage
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Lymphatic Drainage
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Who It's For

Who May Benefit from Lymphatic Drainage Supplements

Lymphatic Drainage supplements like this formula may appeal to anyone interested in traditional herbal approaches to supporting their lymphatic system. You might consider this product if you:

  • Are looking for traditional herbal support for healthy lymphatic flow and drainage
  • Want to promote healthy fluid balance and address occasional water retention
  • Are interested in herbs historically used as "alteratives" to support the body's natural cleansing processes
  • Seek to support overall circulatory and lymphatic well-being as part of a broader wellness routine

Because the traditional evidence behind these herbs can be nuanced, a conversation with a knowledgeable practitioner can be helpful. Our naturopath offers free consultations and can discuss whether Lymphatic Drainage supplements align with your individual wellness goals.

Directions

How to Take Lymphatic Drainage

Take 1 ml (approximately 15–20 drops, 1/4 teaspoon) in water twice daily.

This liquid formula comes in a 2 fl oz bottle, making it easy to measure and add to your daily water. The liquid format allows for quick absorption and simple dose adjustment.

As with any supplement, it's wise to consult your healthcare provider before starting β€” especially if you are pregnant, nursing, taking medications (particularly diuretics, anticoagulants, or hormone-related drugs), or managing a chronic health condition. Several of the herbs in this formula have noted cautions during pregnancy and for individuals on certain medications.

About the author

Written by Greg Howlett

GH

Greg Howlett

Founder

Greg has spent over a decade helping customers choose the right natural-health products. He personally vets every formula we carry and writes these guides to cut through the marketing noise with practical, experience-based advice.

FAQ

Frequently asked questions

What is the lymphatic system and why does it matter?

The lymphatic system is a network throughout your body that helps remove waste from cellular metabolism and maintain fluid balance. When this system functions well, it supports overall health and well-being. Nature's Sunshine Lymphatic Drainage contains nutrients designed to aid the proper dispersion of lymphatic fluid and support this natural process.

What herbs are in this Lymphatic Drainage supplement?

Nature's Sunshine Lymphatic Drainage contains four botanicals: Cleavers aerial parts (300 mg), Red clover blossom extract (300 mg), Stillingia root (300 mg), and Prickly ash bark (300 mg). Each herb has a long history of traditional use as a lymphatic tonic or alterative in Western herbal medicine.

Is there clinical research supporting these herbs for lymphatic health?

The herbs in this formula are primarily supported by long-standing traditional use rather than modern clinical trials. Cleavers and Red clover have centuries of documented use as lymphatic tonics across European, Native American, and other herbal traditions. Laboratory studies have confirmed relevant phytochemical constituents such as flavonoids, iridoids, coumarins, and isoflavones with immunomodulatory and antioxidant activity in vitro. However, no clinical trials specifically evaluating lymphatic outcomes in humans have been published for these individual herbs.

Are there any safety considerations I should know about?

Cleavers is generally regarded as safe at recommended doses but may interact with diuretic medications. Red clover should be avoided by pregnant or nursing women and those with hormone-sensitive conditions, and it may interact with anticoagulant drugs. Stillingia is contraindicated during pregnancy and lactation and can cause gastrointestinal irritation at high doses. Prickly ash is contraindicated during pregnancy and for those on anticoagulant therapy. Consult your healthcare provider before use if you take any medications or have a health condition.

Can I take this supplement alongside other products?

Because several herbs in this formula have noted interactions β€” Cleavers with diuretics, Red clover with anticoagulants and hormone-related medications, and Prickly ash with blood-thinning drugs and antacids β€” it's best to discuss combining supplements or medications with your healthcare provider. Our naturopath is also available for a free consultation to help you think through your supplement routine.

How long does one bottle last?

Each bottle contains 2 fl oz of liquid. At the recommended serving of 1 ml taken twice daily, a single bottle will last approximately 30 days, depending on how precisely you measure each dose.

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