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Liquid Chlorophyll | Benefits, Uses & How It Works

Explore our deep-dive guide on Liquid Chlorophyll β€” what it is, how it supports blood health, immune function, and whole body cleansing, plus FAQs and usage tips.

Overview

What Is Liquid Chlorophyll?

Chlorophyll is the green pigment found in plants that makes photosynthesis possible β€” it absorbs sunlight and converts it into the energy that nourishes all plant life. There are several types, with Chlorophyll a and b representing about 99% of the Chlorophyll species found in edible plants. Rich natural sources include spinach, kale, lettuce, basil, and alfalfa.

Most Liquid Chlorophyll supplements β€” including Nature's Sunshine's Liquid Chlorophyll β€” actually contain sodium copper chlorophyllin, a semisynthetic, water-soluble derivative of Chlorophyll. In chlorophyllin, the central magnesium atom of natural Chlorophyll is replaced with copper, and the fat-soluble phytol tail is removed. This makes the compound dissolve cleanly in water, which is why it works so well in a liquid supplement format.

Chlorophyllin has been used in traditional and clinical settings for more than 50 years, with documented applications including support for natural blood-cleansing processes, internal deodorization, and wound management. Nature's Sunshine harnesses these properties in a convenient 32-oz liquid formula designed to support blood health, immune function, and whole-body cleansing.

How It Works

How Liquid Chlorophyll Supports Your Body

Blood-Cleansing and Detoxification Support. Chlorophyll and chlorophyllin are able to form tight molecular complexes with certain chemicals known or suspected to cause harm β€” including polyaromatic hydrocarbons found in tobacco smoke and heterocyclic amines found in cooked meat. By binding these compounds in the gastrointestinal tract, chlorophyllin may help reduce the amount that reaches susceptible tissues. Research also suggests chlorophyllin may modulate xenobiotic-metabolizing enzymes, including cytochrome P450 inhibition and induction of phase 2 cytoprotective genes β€” complementary detoxification pathways.

Blood Health. Chlorophyll's structural similarity to hemoglobin β€” both share a tetrapyrrole ring structure β€” has historically linked Chlorophyll-rich preparations to blood health. While standard plant Chlorophyll contains magnesium rather than iron, sodium iron chlorophyllin (a related derivative) has shown documented clinical support for hemoglobin levels in research settings. Chlorophyll-rich plants like wheatgrass and alfalfa have been traditionally used to support red blood cell health.

Immune System Support. Chlorophyllin has traditionally been attributed immune-supporting properties. Preclinical evidence points to immunostimulatory effects, potential enhancement of white blood cell production, and anti-inflammatory modulation. Traditional and naturopathic frameworks position Chlorophyll as an immune tonic, though direct human clinical evidence for specific immune outcomes remains limited.

Natural Deodorizer. Chlorophyll has been marketed as an internal deodorant since the 1950s. One study in 62 geriatric nursing home patients found that the administration of chlorophyllin was helpful in controlling body and fecal odors. Another small study in Japanese patients with trimethylaminuria found that oral chlorophyllin significantly decreased urinary trimethylamine.

Antioxidant Activity. The chemical nature of the porphyrin ring allows chlorophylls to function as hydrogen donors, helping prevent oxidative DNA damage and lipid peroxidation by decreasing reactive oxygen species and chelating metal ions.

What's inside

Key Ingredients

Sodium Copper Chlorophyllin β€” 90 mg
Sodium copper chlorophyllin (SCC) is a water-soluble derivative of Chlorophyll in which the central magnesium atom is replaced by copper and the phytol tail is removed. It contains two related copper-containing compounds β€” trisodium copper chlorin e6 and disodium copper chlorin e4 β€” both with porphyrin ring structures. SCC has been used in clinical and traditional applications for over 50 years. Research suggests that chlorophyllin supports the body's defenses against environmental toxins. In a landmark randomized, double-blind, placebo-controlled trial involving 180 adults in Qidong, China β€” a region with high dietary aflatoxin exposure β€” 100 mg of chlorophyllin three times daily for four months produced a 55% reduction in urinary aflatoxin-DNA adduct biomarkers versus placebo. A subsequent Phase 0 human pharmacokinetic study confirmed that both Chlorophyll and chlorophyllin may reduce aflatoxin bioavailability. Studies suggest chlorophyllin supports liver detoxification by binding lipophilic carcinogens and aflatoxins in the GI tract, reducing their absorption and hepatic exposure. Traditional food use of Chlorophyll-rich plants for liver health spans multiple cultures. Chlorophyll's structural similarity to hemoglobin has traditionally linked Chlorophyll-rich preparations to blood health. Sodium iron chlorophyllin (a related derivative) has documented clinical support for hemoglobin: a Phase IV multicenter RCT across 31 hospitals found significant hemoglobin increases in adults and children treated with SIC-containing formulations, while a 2022 meta-analysis of 39 trials further supports efficacy for iron-deficiency anemia. Standard plant Chlorophyll (containing magnesium rather than iron) has been traditionally used to support blood health, though robust human clinical evidence for directly raising hemoglobin with magnesium-centered Chlorophyll is limited. Chlorophyll has been traditionally used as an internal cleanser and detoxifier for decades, based on its documented ability to bind carcinogens, support liver detoxification enzyme systems, and reduce gut-derived toxin absorption. While the aflatoxin chemoprevention data provide a scientific basis for specific toxin binding, the broader concept of whole-body cleansing via Chlorophyll is rooted in traditional use and naturopathic practice. Chlorophyllin has traditionally been attributed immune-supporting properties based on preclinical evidence showing immunostimulatory effects, potential enhancement of white blood cell production, and anti-inflammatory modulation. Direct human clinical evidence for specific immune outcomes is not yet available.
Spearmint Aerial Parts Oil
Spearmint (Mentha spicata) is a flowering, aromatic herb in the Lamiaceae family, native to Europe and southern temperate Asia. The essential oil is distinguished by its signature compound carvone (22–73%) along with limonene (8–31%), giving it a sweeter, milder character than peppermint. Spearmint also contains a rich phenolic fraction, with rosmarinic acid as the dominant non-volatile bioactive. Research suggests spearmint's rosmarinic acid and flavonoids may modulate immune function through antioxidant, anti-inflammatory, antibacterial, and immunosuppressant mechanisms documented in preclinical studies. Rosmarinic acid has specifically demonstrated immunosuppressant activity, including induction of apoptosis of activated T cells from rheumatoid arthritis patients in preclinical models. Spearmint has a long traditional history as a digestive aid, flavoring agent, and aromatic herb used across cultures β€” from ancient Roman baths to traditional Iranian medicine for digestive complaints, and in Moroccan ethnobotanical practice for a variety of common health concerns.
Liquid Chlorophyll
Liquid Chlorophyll
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Liquid Chlorophyll
Liquid Chlorophyll
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Who Benefits

Who Is Liquid Chlorophyll For?

Liquid Chlorophyll may appeal to a wide range of adults looking for gentle, plant-based internal support. It's particularly well-suited for those interested in:

  • Blood health support β€” anyone drawn to the traditional connection between Chlorophyll and healthy blood, given its structural similarity to hemoglobin
  • Whole-body cleansing β€” individuals looking for a daily internal cleanse rooted in Chlorophyll's documented ability to bind certain unwanted compounds in the GI tract
  • Immune system encouragement β€” those seeking to complement their wellness routine with a traditionally used immune tonic
  • Internal freshness β€” people interested in Chlorophyll's historical use as a natural internal deodorizer

Because this is a simple, unflavored liquid that mixes into cold water, it's easy to incorporate into almost any daily routine. If you're not sure whether Liquid Chlorophyll is a good fit for your wellness goals, our naturopath is available for a free consultation β€” just reach out.

Note: Since the safety of Chlorophyll or chlorophyllin supplements has not been tested in pregnant or lactating women, they should be avoided during pregnancy and lactation. Individuals with rare disorders of copper metabolism, such as Wilson's disease, should limit exposure to copper additives, including supplemental sodium copper chlorophyllin.

Usage

How to Take Liquid Chlorophyll

Take 2 tablespoons (30mL) in an 8 fl oz glass of cold water daily. Refrigerate after opening.

The formula mixes easily into water, creating a mild, green-tinted drink. Many people enjoy it first thing in the morning as part of their daily wellness routine.

When taken orally, supplemental chlorophyllin may cause green discoloration of urine or feces, or yellow or black discoloration of the tongue. There have also been occasional reports of diarrhea. These effects are generally harmless. Oral chlorophyllin may also result in false positive results on guaiac card tests for occult blood β€” worth mentioning to your healthcare provider if you're undergoing such testing.

About the author

Written by Greg Howlett

GH

Greg Howlett

Founder

Greg has spent over a decade helping customers choose the right natural-health products. He personally vets every formula we carry and writes these guides to cut through the marketing noise with practical, experience-based advice.

FAQ

Frequently asked questions

Is Liquid Chlorophyll the same as the Chlorophyll found in plants?

Not exactly. Most Liquid Chlorophyll supplements, including this one, contain sodium copper chlorophyllin β€” a semisynthetic, water-soluble derivative of natural Chlorophyll. In chlorophyllin, the central magnesium atom found in plant Chlorophyll is replaced with copper, and the fat-soluble phytol tail is removed. This makes it dissolve cleanly in water, which natural Chlorophyll cannot do. Chlorophyllin has been in clinical and traditional use for more than 50 years.

Does Liquid Chlorophyll really help with body odor?

Chlorophyll has been marketed as an internal deodorant since the 1950s. One study in 62 geriatric nursing home patients found chlorophyllin helpful in controlling body and fecal odors. A small study in Japanese patients with trimethylaminuria found that oral chlorophyllin significantly decreased urinary trimethylamine. However, the evidence in healthy individuals is largely drawn from small, older studies, and modern controlled research on general body odor in healthy people is limited.

Are there any side effects of taking Liquid Chlorophyll?

Natural chlorophylls are not known to be toxic, and no toxic effects have been attributed to chlorophyllin despite more than 50 years of clinical use. Common, harmless effects include green discoloration of urine or feces, or yellow or black discoloration of the tongue, and occasional diarrhea. Those who are pregnant, lactating, or have Wilson's disease or other copper metabolism disorders should avoid chlorophyllin supplements. If you take medications β€” particularly methotrexate or other drugs processed by the liver β€” consult your healthcare provider before starting supplementation.

How does chlorophyllin support blood health?

Chlorophyll's tetrapyrrole ring structure is remarkably similar to hemoglobin's heme group β€” with magnesium at the center of Chlorophyll versus iron in hemoglobin. This structural kinship has led to a longstanding traditional association between Chlorophyll-rich preparations and blood health. While sodium iron chlorophyllin (a related derivative containing iron) has clinical evidence supporting hemoglobin levels, the standard sodium copper chlorophyllin found in most Liquid Chlorophyll supplements is traditionally rather than clinically linked to blood support.

Can I take Liquid Chlorophyll with medications?

A case of delayed methotrexate clearance was reported following administration of a Chlorophyll-containing supplement, suggesting a potential interaction with at least one chemotherapy agent. Chlorophyllin can also form molecular complexes with various compounds, and it is not yet known whether this mechanism might affect the absorption of co-administered medications. If you take prescription medications, we recommend speaking with your healthcare provider. Our naturopath is also available for a free consultation to discuss your specific situation.

What is the difference between Chlorophyll and chlorophyllin?

Chlorophyll is the natural, fat-soluble green pigment found in plants. It has a magnesium atom at its center and a long phytol tail that makes it insoluble in water. Chlorophyllin is a semisynthetic derivative in which the magnesium is replaced with copper and the phytol tail is removed, making it water-soluble. This is why liquid supplement products use chlorophyllin β€” it dissolves readily into water. Both share the same porphyrin ring structure responsible for many of Chlorophyll's documented properties.

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