Magnesium Malate – Nervous System & Bone Support

Magnesium is the fourth most abundant cation in the human body and a critical cofactor in hundreds of enzymatic reactions that regulate energy metabolism, neuromuscular function, cardiovascular health, bone integrity, and psychological well-being. Nature's Sunshine Magnesium provides nervous system support and assists in a variety of bodily functions, delivering 250 mg of Magnesium per tablet.

Used by several hundred enzymes in their daily tasks, Magnesium is found in the bones, soft tissues, and blood. It helps metabolize various nutrients such as vitamin C, Phosphorus, potassium, and sodium. Calcium and Magnesium are nutritional partners and work best when taken together — which is why this formula includes both minerals.

Nature's Sunshine Magnesium comes in capsules of Magnesium oxide and Magnesium amino acid chelate in a base of Licorice root, Kelp plant, Peppermint leaves, and White willow bark. This thoughtful combination provides Magnesium malate alongside supportive botanicals that have been used in traditional herbal practice for centuries.

Magnesium is a cofactor in more than 300 enzyme systems that regulate diverse biochemical reactions in the body, including protein synthesis, muscle and nerve function, blood glucose control, and blood pressure regulation. It is required for energy production, oxidative phosphorylation, and glycolysis — the fundamental processes that keep every cell running.

For nervous system health, Magnesium modulates neuronal excitability through voltage-gated Calcium antagonism and NMDA receptor blockade. Research suggests that deficiency is associated with increased risk of neurological symptoms, and supplementation supports normal nerve function.

For bone density, Magnesium is involved in bone formation and influences the activities of osteoblasts and osteoclasts. It also affects the concentrations of both parathyroid hormone and the active form of vitamin D, which are major regulators of bone homeostasis. Observational data from large cohort studies found higher Magnesium intake associated with 2–3% greater bone density in women.

As a muscle relaxant, Magnesium is an essential mineral co-factor for ATP synthesis and muscle contraction. Magnesium deficiency impairs muscle relaxation — muscles contract normally but may struggle to fully release when levels are low. A 2024 systematic review found Magnesium supplementation reduced muscle soreness, improved performance and recovery, and exerted a protective effect on muscle damage in physically active individuals.

Emerging evidence confirms that nearly two-thirds of the population in the western world is not achieving the recommended daily allowance for Magnesium, making thoughtful supplementation particularly relevant. If you're unsure whether Magnesium malate is right for your needs, our naturopath is available for a free consultation.

This formula may be a good fit for adults looking to support their nervous system, maintain healthy bones, and promote comfortable muscle function. Because Magnesium is necessary for the function of over 300 enzymes — and research suggests that between 56 and 68% of Americans do not obtain enough Magnesium in their diet — many people may benefit from thoughtful supplementation.

Adults concerned about bone density may find this formula particularly relevant, since Magnesium, Calcium, and Phosphorus all play recognized roles in skeletal mineralization. The combination of all three minerals in one tablet supports a comprehensive approach to bone health.

Those who experience occasional muscle tension or cramps may also appreciate this formula. Magnesium boosts energy production and promotes proper elimination, while its role as a muscle relaxant is well-recognized in nutritional science.

Older adults may benefit as well, since Magnesium absorption and retention can decrease with age. The diets of most people in the United States provide less than recommended amounts of Magnesium, and men older than 70 and teenage girls are most likely to have low intakes.

If you're not sure whether this supplement fits your situation — especially if you take medications — our naturopath offers free consultations and can help you think it through.

Take 1 tablet daily with a meal. Each bottle contains 180 tablets.

Taking Magnesium with food supports absorption and helps minimize the occasional digestive discomfort that some people experience with mineral supplements. Magnesium supplements can cause softening of stool in some individuals, and side effects are generally more common with inorganic forms such as Magnesium oxide.

Because Calcium and Magnesium are nutritional partners that work best when taken together, this formula conveniently provides both in a single tablet. Vitamin D also helps the body better absorb Calcium, so ensuring adequate vitamin D status may further support the benefits of this supplement.