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Magnesium Lotion & Topical Magnesium Support

Explore Magnesium lotion and oral Magnesium supplements for nervous system health, bone density, and muscle cramps. Learn about key ingredients and benefits.

Understanding Magnesium

What Is Magnesium and Why Does It Matter?

Magnesium is the fourth most abundant cation in the human body and a critical cofactor in more than 300 enzyme systems that regulate energy metabolism, neuromuscular function, cardiovascular health, bone integrity, and psychological well-being. Whether you're exploring Magnesium lotion for topical application or considering an oral Magnesium supplement, understanding this mineral's far-reaching role can help you make an informed choice.

Nature's Sunshine Magnesium provides nervous system support and assists in a variety of bodily functions. Used by several hundred enzymes in their daily tasks, Magnesium is found in the bones, soft tissues, and blood. It helps metabolize various nutrients such as vitamin C, Phosphorus, potassium, and sodium.

Emerging evidence confirms that nearly two-thirds of the population in the western world is not achieving the recommended daily allowance for Magnesium—a deficiency problem contributing to various health conditions. Early signs of Magnesium deficiency include loss of appetite, nausea, fatigue, and weakness. As deficiency worsens, numbness, tingling, muscle cramps, seizures, and abnormal heart rhythms can occur.

Delivery Methods

Magnesium Lotion vs. Oral Magnesium Supplements

Many people searching for Magnesium lotion are looking for ways to support their Magnesium levels through the skin. Topical Magnesium products like lotions and creams have grown popular for targeted muscle comfort. However, well-studied oral Magnesium supplements also offer systemic support for muscles, bones, and the nervous system.

Nature's Sunshine Magnesium comes in 250 mg capsules of Magnesium oxide and Magnesium amino acid chelate in a base of Licorice root, Kelp plant, Peppermint leaves, and White willow bark. Calcium and Magnesium are nutritional partners and work best when taken together—this formula includes 40 mg of Calcium alongside the Magnesium.

If you're weighing Magnesium lotion against an oral supplement—or wondering whether to use both—our naturopath is available for a free consultation to help you determine what may work best for your individual needs.

Qué contiene

Key Ingredients

Magnesium — 250 mg
Magnesium is the cornerstone of this formula. It is a cofactor in more than 300 enzyme systems that regulate protein synthesis, muscle and nerve function, blood glucose control, and blood pressure regulation. It is required for energy production, oxidative phosphorylation, and glycolysis. Research suggests that Magnesium is an essential cofactor in bone mineral metabolism and is required for vitamin D activation; observational data from large cohort studies found higher Magnesium intake associated with 2–3% greater bone density in women. As a natural NMDA receptor antagonist, Magnesium modulates synaptic transmission and neuronal excitability, supporting normal nerve function. Regarding muscle cramps, Magnesium deficiency impairs muscle relaxation—muscles contract normally but may struggle to fully release when levels are low. A 2024 systematic review found Magnesium supplementation reduced muscle soreness, improved performance and recovery, and exerted a protective effect on muscle damage in physically active individuals. Magnesium also supports electrolyte balance as one of the seven major electrolytes, foundational to sodium-potassium ATPase function and all electrolyte transport.
Calcium — 40 mg
Calcium is the most abundant mineral in the human body and a nutritional partner to Magnesium. More than 99% of the body's Calcium is stored in bone as hydroxyapatite, providing skeletal strength. Research suggests that Calcium supplementation significantly improves bone mineral density, particularly in people under 35 building peak bone mass. Combined with vitamin D, it may help attenuate bone loss in older adults. Calcium is also essential for muscle contraction and relaxation—hypocalcemia is recognized as a cause of muscle cramps, tetany, and spasms. In the nervous system, Calcium ions stabilize membrane potential and control the excitability of neurons, serving as a universal second messenger in neurotransmission. As one of the seven primary electrolytes, Calcium is critical for nerve transmission, enzyme activity, and blood coagulation.
Phosphorus — 30 mg
Phosphorus is the second most abundant mineral in the human body, with approximately 85% residing in bones and teeth as hydroxyapatite. Together with Calcium, it forms the mineral matrix that provides bones and teeth with structural integrity and strength. Phosphorus plays essential roles in producing and storing energy through phosphate bonds (ATP), buffering blood pH, regulating gene transcription, and activating enzyme catalysis. Phospholipids containing Phosphorus are primary components of neuronal cell membranes and are required for synaptic neurotransmission. Skeletal muscles are the primary consumers of phosphate-dependent energy—adequate Phosphorus is required for contraction, recovery, and maintenance.
Kelp leaf and stem
Kelp is a brown seaweed that has been used traditionally for over 1,500 years in Asian cultures and by Pacific Northwest Indigenous Peoples for a wide range of health concerns. It is a rich source of vitamins and minerals, including dietary iodine. Kelp's primary established mechanism of action in humans is the delivery of bioavailable dietary iodine, which supports thyroid hormone production. The main groups of biologically active compounds in Kelp include polysaccharides such as alginic acid, laminarin, and fucoidan, along with minerals including Magnesium, potassium, Calcium, and iron. Historically, Kelp was used to treat goiter-related diseases and was incorporated into traditional Chinese medicine prescriptions.
Licorice root
Licorice root (Glycyrrhiza glabra) has been used worldwide as a medicine for over 4,000 years. It appears in approximately 60% of traditional Chinese medicine prescriptions as an agent in the treatment of fatigue, dry cough, and bronchitis. Historically, licorice has been used in traditional medicine to treat gastrointestinal problems such as gastritis and peptic ulcers, and it has also been traditionally used for respiratory infections, coughs, and sore throats. The German Commission E approves the use of licorice for catarrhal conditions of the upper respiratory tract. The main constituent of the roots is glycyrrhizin, a triterpenoid saponin, along with flavonoids and polyphenols.
Peppermint leaves
Peppermint (Mentha × piperita) has been used as a remedy for indigestion since ancient Egyptian times. Dried Peppermint leaves were found in Egyptian pyramids dating back to 1000 BC. The main constituents are menthol and menthone. Peppermint oil contains L-menthol, which blocks Calcium channels in smooth muscle, producing antispasmodic effects on the gastrointestinal tract. The German Commission E approved Peppermint leaf for spastic complaints of the gastrointestinal tract. During the eighteenth century, Peppermint became popular in Western Europe as a folk remedy for nausea, vomiting, and respiratory infections.
White willow bark
White willow bark (Salix alba) has been traditionally used as a painkiller and antipyretic for more than 3,500 years, with records dating to the Sumerians and Egyptians. It contains salicin, a prodrug that is metabolized to salicylic acid—the compound that historically inspired the development of aspirin. White willow bark is traditionally used for muscle pain and soreness across European, Native American, and Chinese herbal traditions. Its COX-inhibitory mechanism is pharmacologically applicable to muscle inflammation and soreness. In traditional medicine, Commission E approves it for fever and pain conditions, and it has historically been used for headaches, arthritis, and general pain relief.
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Who Benefits

Who May Benefit from Magnesium Support?

Whether you arrived here researching Magnesium lotion or oral Magnesium, this supplement may be a good fit for several groups. Adults whose diets provide less than the recommended amounts of Magnesium—which research suggests includes the majority of Americans—may benefit from supplementation. Men older than 70 and teenage girls are most likely to have low intakes.

People experiencing occasional muscle cramps or tension may find Magnesium particularly relevant, since Magnesium deficiency impairs muscle relaxation. Those focused on bone density may also appreciate the Calcium-Magnesium partnership in this formula—Calcium and Magnesium are nutritional partners and work best when taken together.

Older adults may be especially susceptible to Magnesium deficiency due to decreased absorption from food, increased medication use, and potential dietary restrictions. If you're unsure whether a Magnesium supplement is right for your situation, our naturopath offers free consultations to help you evaluate your needs.

How to Take

Directions for Use

Take 1 tablet daily with a meal.

Each serving provides 250 mg of Magnesium along with 40 mg of Calcium, 30 mg of Phosphorus, and a supportive base of Licorice root, Kelp plant, Peppermint leaves, and White willow bark. The bottle contains 180 tablets.

Sobre el autor

Escrito por Greg Howlett

GH

Greg Howlett

Founder

Greg has spent over a decade helping customers choose the right natural-health products. He personally vets every formula we carry and writes these guides to cut through the marketing noise with practical, experience-based advice.

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Preguntas frecuentes

Is Magnesium lotion the same as an oral Magnesium supplement?

No. Magnesium lotion is applied topically to the skin, while oral supplements like Nature's Sunshine Magnesium are taken by mouth as tablets. Oral Magnesium has been extensively studied for its roles in nervous system health, bone density, and muscle function. This formula delivers 250 mg of Magnesium per tablet alongside Calcium, Phosphorus, and a supportive herbal base.

Why are Calcium and Magnesium included together in this formula?

Calcium and Magnesium are nutritional partners and work best when taken together. Magnesium is required for vitamin D activation and Calcium metabolism, while Calcium is the primary mineral constituent of bone. Together they support bone density, muscle function, and electrolyte balance.

How many enzymes does Magnesium support?

Magnesium is a cofactor in more than 300 enzyme systems in the body, regulating diverse biochemical reactions including protein synthesis, muscle and nerve function, blood glucose control, and blood pressure regulation. It is also required for energy production, oxidative phosphorylation, and glycolysis.

Can Magnesium help with muscle cramps?

Magnesium deficiency impairs muscle relaxation—muscles contract normally but may struggle to fully release when levels are low. Research on Magnesium for muscle cramps shows mixed results: Cochrane reviews found it unlikely to provide meaningful cramp prophylaxis in older adults with idiopathic cramps, but evidence for pregnancy-associated leg cramps remains conflicting. A 2024 systematic review did find that Magnesium supplementation reduced muscle soreness and supported recovery in physically active individuals.

What role does Magnesium play in bone health?

Magnesium is involved in bone formation and influences the activities of osteoblasts and osteoclasts. It also affects concentrations of both parathyroid hormone and the active form of vitamin D, which are major regulators of bone homeostasis. Research suggests that people with higher levels of Magnesium may have higher bone mineral density, which is important in helping reduce the risk of bone fractures.

What forms of Magnesium are in this supplement?

Nature's Sunshine Magnesium contains Magnesium oxide and Magnesium amino acid chelate. Magnesium oxide is the most concentrated form by weight. The formula also includes a supportive base of Licorice root, Kelp plant, Peppermint leaves, and White willow bark.

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Magnesium Lotion & Topical Magnesium Support