Semecarpus anacardium, commonly known as the "marking nut," has a long history of use in traditional Ayurvedic medicine. Its use for supporting or treating injuries primarily comes from traditional practices rather than robust scientific validation. In Ayurvedic texts, the oil or preparations made from the nut have been applied externally to aid in healing wounds, reducing inflammation, and alleviating pain associated with injuries. The rationale for its use is based on its purported anti-inflammatory, analgesic, and antimicrobial properties, which are described in classical Ayurvedic literature.

Scientific studies on Semecarpus anacardium are limited, but some laboratory research has reported anti-inflammatory and wound-healing activities in animal models. For example, ethanolic extracts have demonstrated some efficacy in promoting wound contraction and increasing the rate of epithelialization in rats. However, these findings are preliminary and not sufficient to provide strong clinical recommendations. Moreover, the raw nut is known to be irritant and even toxic, necessitating caution in its preparation and use.

In summary, the use of Semecarpus anacardium for injuries is primarily justified by traditional knowledge, with only limited and low-quality scientific evidence available to date. Its traditional application continues in some herbal and Ayurvedic settings, but it should be approached with caution due to potential adverse effects.