Calendula officinalis (marigold) has a long history of traditional use for wound healing, and its topical application for injuries is supported by a moderate amount of scientific evidence. Calendula contains several biologically active compounds, including flavonoids, triterpenoids, and carotenoids, which have demonstrated anti-inflammatory, antimicrobial, and wound-healing properties in preclinical studies.

Clinical trials, though generally small and of variable quality, suggest that calendula ointments or creams can promote faster healing of minor wounds, reduce inflammation, and decrease the risk of infection. For example, a randomized controlled trial published in Complementary Therapies in Medicine (2013) found that calendula significantly improved healing in patients with venous leg ulcers compared to standard care. Other studies have shown beneficial effects for minor burns and post-surgical wounds, though results are not always consistent.

Mechanistically, calendula is thought to enhance granulation tissue formation, stimulate angiogenesis, and modulate inflammatory cytokines, all of which are important for injury recovery. Safety profiles are generally favorable, with few reports of adverse effects, mainly limited to rare allergic reactions.

In summary, while calendula’s use in injury treatment is rooted in tradition, there is moderate scientific evidence supporting its topical application for minor wounds and injuries. However, larger, high-quality clinical trials are needed to fully confirm its efficacy and establish standardized dosing protocols.