Evidence supporting the use of: Vitamin C
For the body system: Circulatory System

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin C (ascorbic acid) is scientifically recognized for its role in maintaining the health of the circulatory system, particularly through its antioxidant properties and its contribution to collagen synthesis. Collagen is an essential structural protein in blood vessels, helping to maintain their integrity and elasticity. Deficiency in vitamin C (as seen in scurvy) leads to weakened blood vessels, bleeding, and impaired wound healing, clearly demonstrating its importance for vascular health.

Additionally, vitamin C acts as an antioxidant, reducing oxidative stress that can damage the endothelial lining of blood vessels and contribute to atherosclerosis. Some clinical studies suggest that higher vitamin C intake is associated with improved endothelial function and lower blood pressure, both of which support overall cardiovascular health. However, large-scale randomized controlled trials have not consistently demonstrated that vitamin C supplementation reduces major cardiovascular events like heart attacks or strokes in the general population. Most benefits appear to be in populations with low baseline vitamin C status or in the prevention of deficiency-related vascular problems.

In summary, there is scientific validation for vitamin C’s role in supporting the circulatory system, particularly in maintaining blood vessel health and integrity. However, evidence for its use in preventing or treating cardiovascular disease in well-nourished individuals is moderate, not strong, hence a rating of 3.

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Other ingredients that support Circulatory System

ajoene
alfalfa
algal oil
alpha-carotene
alpha-glycosyl isoquercitrin
alpha-linolenic acid (ALA)
amino acids
anchovies
anthocyanins
apple
arjun tree
artichoke
ashwagandha
astaxanthin
astragalus
barley
basil
beet
berberine
bergamot
Beta-Glucan
bilberry
black cumin
black currant
black garlic
sesame
black tea
blackberry
blueberry
bonito peptide
bovine liver
broccoli
brussel sprouts
burdock
butcher's broom
caffeine
calamari oil
calcium
campesterol
canola oil
capsaicinoids
cassia bark
catechins
caterpillar mushroom
cauliflower
celery
cherry
chia seed
Chinese salvia root
chlorella
chokeberry
cinnamon
citrus bioflavonoids
citrus sinensis (proprietary)
coenzyme Q10 (CoQ10)
coleus forskohlii
collard
copper
cottonseed oil
cordyceps
turmeric
curcumin
cuspidatum root
d-alpha tocopherol
dandelion
DHA (docosahexaeonic acid)
diallyl disulfide (DADS)
diallyl trisulfide (DATS)
dog rose
dong quai root
DPA (docosapentaenoic acid)
eleuthero
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
ethanol
fennel
fenugreek
fiber blend (proprietary)
fisetin
fish oil
fish protein
flavonols
flaxseed
forskohlii root
fruit and vegetable blend (proprietary)
gamma linolenic acid (GLA)
gamma tocopherol
garlic bulb
ginger
ginkgo biloba
ginseng
gokhru
gooseberry
gotu kola
grape
greek mountain tea
onion
green tea
greens blend (proprietary)
guggul
hawthorn
hesperetin
hesperidin
hibiscus
horse chestnut
iron
knotweed
Japanese sophora
kale
krill oil
kudzu
l-arginine
l-carnitine
l-citrulline
l-taurine
lignans
linoleic acid (LA)
luteolin
lycopene
mackerel
magnesium
mango
mangosteen
maqui berry
marine lipid
matcha
moringa
motherwort
mustard seed
naringin
nattokinase
nattozimes
nettle
niacin (vitamin B3)
niacinamide (vitamin B3)
nicotinamide riboside
oat
okra
oleic acid
olive
omega-3 fatty acids
omega-6 fatty acids
omega-9 fatty acids
orange
oyster mushroom
palmitoleic acid
pantethine
parsley
phenolic acids
phytosterols
pine bark
plant sterols
policosanol
pomegranate
pomelo
potassium
quercetin
quinoa
raspberry
red yeast rice
rehmannia glutinosa
reishi mushroom
resveratrol
rhizome
rose hips
rosemary
rutin
safflower oil
sardines
scrophularia root
secoisolariciresinol diglucoside
selenium
black ginger
sitostanol
soybean
spinach
spirulina
sterols
strawberry
sulforaphane glucosinolate
thiamin (vitamin B1)
tocotrienols
tomato
trans-pterostilbene
trimethylglycine (TMG)
triphala
almond fruit
ubiquinol
Urolithin A
vegetable and fruit blend (proprietary)
vegetable blend (proprietary)
vinpocetine
vitamin B
vitamin C
vitamin D
vitamin D3
vitamin E
vitamin K
seaweed
water
watercress
watermelon
wheat grass
mulberry
β-nicotinamide mononucleotide (NMN)
sarsaparilla
red clover
suma
jiaogulan
tangerine
gastrodia
lobelia
capsicum
hedychium spicatum
inula racemosa
punarnava
commiphora
rubia cordifolia
bee pollen
peony
lingzhi
lingusticum wallichii
yarrow
prickly ash
morus
lemongrass
sodium salt
ferulic acid
chrysanthemum
eucommia
ganoderma
zanthoxylum
electrolytes blend (proprietary)
terpene lactones
polyphenols
trace minerals
purslane
barrenwort
camphor oil
shepherd's purse
yerba mate
wheat germ
noni
wood betony
nopal
amaranth
herbal blend (proprietary)
Sichuan pepper
algae
yohimbe
kidney beans
cocoa
AMP-activated protein kinase (AMPK)
cayenne pepper
cayenne pepper
ashitaba
arnica
1,3,7-Trimethylpurine-2,6-dione
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
Arjuna
Arginine Alpha Ketoglutarate
Animal Tissue
Arginine Creatine
Arginine nitrate
Asiaticoside
Angelica
Aronia melanocarpa
Allicin
Arginine malate
Arginine aspartate
Achyranthes
Auricularia
Avocado
Adrenergic amines
Alpha-Lipoic Acid
Astragaloside
Adrenaline
Aescin
anthocyanidins
Ampelopsin
Asteracea
Allyl Sulfide
Alpha phytosterol
Acetylsalicylic acid
Algal protein
Arjunic Acid
Alliin
anthocyanosides
Ashoka
Allium tuberosum
Apocynin
Arginine silicate
Arjunolic acid
Animal protein
Bee Propolis
Betony
Black Seed
Butylphthalide
Baikal Skullcap
Bidens pilosa
Brutieridin
Breadnut
Brassica
Bayleaf
Bran
Black galingale
Beef
Beef liver
Berberis (unspecified)
Baicalein
Benfotiamine
berry
Bethroot
Brazil nut
Ba Ji Tian
Bioflavonoids
Bee products
Borage
banana
Baicalin
Buckwheat
Bignay
Boerhavia diffusa
Bottle gourd
bugleweed
Borneol
Chia seed
Caffeic Acid
Camellia sinensis
Centella triterpenes
Cowpea
California chia
Cinnamomum
Clary sage
Chinese Mountain Ant
Cyanobacteria
Carqueja
Clerodendrum trichotomum
Capsinoids
Catalpol
Camelina Oil
Cod Liver Oil
Cortisol
Codonopsis
Coriander
Chive
Cyathula
Cyanidin
chlorogenic acid
Curcuminoid
Citrus
Capsaicin
Catecholamine
Cruciferous
Curcumen
Centella asiatica
Coca
Chocolate
Chard
Cissus sicyoides
Curcuma
Carnosol
Calanus finmarchicus
Catuaba
C-Phycocyanin
cypress
Cowslip
Cranesbill
Cornus
Cha de bugre
Chinese Thoroughwax
Chestnut
Cynodon dactylon
Collinsonia
Carthamus
cola nut
Casearia sylvestris
Currant
Docosahexaenoic Acid
Diallyl sulfide
Dihydrocapsaicin
Diosmin
Dismutase
Danshen
Delphinidin
Dodeca-2E, 4E-Dienoic Acid Isobutylamide
Dextran
Deer Velvet
Dong Quai
Dihydrolipoic Acid
Date
Dwarf Nettle
Dulse
D-Ribose
Diterpenes
Digitalis
Dimorphandra gardneriana
Diosmetin
epicatechin
E-Viniferin
Ephedra
Erigeron
Eriocitrin
Egg
European hazel
Ergothioneine
Elk antler
Emblicanin
Eicosapentaenoic Acid
Essential Oil Blend
Ephedrine
Escin
Eucommia ulmoides
Echium
Ecklonia
Garlic
Mustard
Mistletoe
Periwinkle
Pistachio
Rose
Snakeroot (unspecified)
salt
Soy Protein
Sumac
Vervain
walnut
yohimbine

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Nature's Sunshine MultiVitamin & Mineral (SynerPro)
Nature's Sunshine MultiVitamin & Mineral (Time Release)
Nature's Sunshine Natural Changes
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Nature's Sunshine Nature's Harvest
Nature's Sunshine Nervous System (30 Day Program)
Nature's Sunshine Nutri-Calm
Nature's Sunshine Nutri-Calm
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Nature's Sunshine Power Beets To-Go Packs
Nature's Sunshine Power Greens
Nature's Sunshine Power Greens To-Go
Nature's Sunshine Skeletal Strength
Nature's Sunshine Solstic Twenty-Four
Nature's Sunshine Solstic Immune
Nature's Sunshine Solstic Revive
Nature's Sunshine Structural System (30 Day Program)
Nature's Sunshine Super Supplemental
Nature's Sunshine Super Supplemental (Without Iron)
Nature's Sunshine Super Trio
Nature's Sunshine Vari-Gone
Nature's Sunshine Vitamin C (1000 mg, Time Release)
Nature's Sunshine Vitamin C (1000 mg, Time Release)
Nature's Sunshine Vitamin C Ascorbates
Nature's Sunshine Chewable Vitamin C
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