Polygonatum, commonly known as Solomon’s Seal, has a long history of use in traditional Chinese medicine (TCM) and other herbal traditions. In TCM, Polygonatum species (such as Polygonatum sibiricum and Polygonatum odoratum) are classified as "tonics" and are believed to nourish "Yin," moisten dryness, and support overall vitality. While the concept of directly supporting the adrenal glands is not a classical term in TCM, many modern herbalists interpret Yin tonic herbs as supportive of adrenal health, especially in cases of fatigue or "burnout"—conditions sometimes associated with adrenal insufficiency in Western paradigms.

There is, however, a lack of direct scientific research linking Polygonatum to measurable improvements in adrenal function or hormonal regulation in humans. Most available studies focus on its antioxidant, anti-inflammatory, and immunomodulatory effects. The connection to adrenal support is therefore extrapolated from traditional energetic frameworks rather than validated by clinical trials or pharmacological studies specific to the adrenal glands.

In summary, the use of Polygonatum to support the adrenal glands is rooted primarily in traditional herbal practices and interpretations, not in robust scientific evidence. While it is valued for promoting vitality and resilience in traditional systems, the direct evidence for adrenal-specific benefits remains limited to traditional understanding and anecdotal use.