Magnesium Supplement | Nervous System & Bone Support

Magnesium is the fourth most abundant cation in the human body and a critical cofactor in more than 300 enzyme systems that regulate energy metabolism, neuromuscular function, cardiovascular health, bone integrity, and more. Despite its importance, emerging evidence confirms that nearly two-thirds of the population in the Western world is not achieving the recommended daily allowance for Magnesium — a shortfall that may contribute to a range of health concerns.

This Nature's Sunshine Magnesium supplement provides 250 mg of Magnesium per tablet, combining Magnesium oxide and Magnesium amino acid chelate in a supportive base of Licorice root, Kelp plant, Peppermint leaves, and White willow bark. The formula is designed to promote nervous system health, support bone density, and help address occasional muscle cramps — three areas where Magnesium plays a well-documented physiological role.

Because Calcium and Magnesium are nutritional partners and work best when taken together, this formula also includes 40 mg of Calcium and 30 mg of Phosphorus, two minerals that collaborate with Magnesium in bone mineralization and enzyme function. If you have questions about whether a Magnesium supplement fits your wellness routine, our naturopath is available for a free consultation.

Magnesium is necessary for the function of roughly 300 enzymes involved in protein synthesis, muscle and nerve function, blood glucose control, and blood pressure regulation. It is required for energy production, oxidative phosphorylation, and glycolysis — processes that fuel every cell in the body.

Nervous system: Magnesium modulates neuronal excitability through voltage-gated Calcium antagonism and N-methyl-D-aspartate (NMDA) receptor blockade. Research suggests that adequate Magnesium status supports normal nerve signaling and may help maintain a calm, balanced nervous system.

Bone density: Magnesium is involved in bone formation and influences the activities of osteoblasts and osteoclasts. It also affects concentrations of both parathyroid hormone and the active form of vitamin D, which are major regulators of bone homeostasis. Observational data from large cohort studies found higher Magnesium intake associated with greater bone density in women.

Muscle relaxation: As an essential mineral cofactor for ATP synthesis and intracellular Calcium transport, Magnesium supports normal muscle contraction and relaxation. Magnesium deficiency impairs muscle relaxation — muscles contract normally but may struggle to fully release when levels are low.

Energy production: Mg²⁺ plays a pivotal role in ATP synthesis catalyzed by ATP synthases, making Magnesium indispensable for cellular energy generation across virtually all tissues.

Proper elimination: Magnesium supplements often promote softening of stool, which may support regular, comfortable elimination.

Because the diets of most people in the United States provide less than the recommended amounts of Magnesium, a broad range of adults may find a Magnesium supplement helpful. Men older than 70 and teenage girls are most likely to have low intakes, and it is estimated that between 56% and 68% of Americans do not obtain enough Magnesium daily to meet the recommended dietary allowance.

This formula may be especially relevant for individuals interested in supporting nervous system health, maintaining healthy bone density, or addressing occasional muscle cramps. Magnesium's role as a cofactor for ATP synthesis also means it may appeal to those who want to promote healthy energy production.

As we age, Magnesium absorption and retention can decrease, leading to potential deficiency and its consequences — including fatigue, muscle cramps, and weakened bones. Older adults, individuals with gastrointestinal concerns, and those on certain long-term medications such as proton pump inhibitors or diuretics may be at elevated risk for Magnesium inadequacy.

If you're unsure whether a Magnesium supplement is right for you, our naturopath offers free consultations to help you explore your options.

Take 1 tablet daily with a meal.

Each bottle contains 180 tablets. Magnesium supplements may cause softening of stool in some individuals, which is generally a mild and expected effect. As with any dietary supplement, consult with a healthcare professional before starting if you are pregnant, nursing, taking medication, or have a medical condition.