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Magnesium Hydroxide Guide | Caring Sunshine

Discover how Magnesium hydroxide supports nervous system health, bone density, and muscle relaxation. Learn about key ingredients, benefits, and usage tips.

Essential Mineral

Understanding Magnesium Hydroxide and Why It Matters

Magnesium is the fourth most abundant cation in the human body and a critical cofactor in hundreds of enzymatic reactions that regulate energy metabolism, neuromuscular function, cardiovascular health, bone integrity, and psychological well-being. It is naturally present in many foods, including green leafy vegetables, nuts, seeds, whole grains, fish, and dairy products.

Nature's Sunshine Magnesium provides nervous system support and assists in a variety of bodily functions. Used by several hundred enzymes in their daily tasks, Magnesium is found in the bones, soft tissues, and blood. It helps metabolize various nutrients such as vitamin C, Phosphorus, potassium, and sodium.

Despite its essential roles, emerging evidence confirms that nearly two-thirds of the population in the western world is not achieving the recommended daily allowance for Magnesium β€” a deficiency problem contributing to various health conditions. Men older than 70 and teenage girls are most likely to have low intakes, and as we age, Magnesium absorption and retention can decrease, leading to deficiency and health consequences.

Calcium and Magnesium are nutritional partners and work best when taken together. Nature's Sunshine Magnesium comes in 250 mg capsules of Magnesium oxide and Magnesium amino acid chelate in a base of Licorice root, Kelp plant, Peppermint leaves, and White willow bark.

How It Works

How Magnesium Hydroxide Supports Your Body

Magnesium is a cofactor in more than 300 enzyme systems that regulate diverse biochemical reactions in the body, including protein synthesis, muscle and nerve function, blood glucose control, and blood pressure regulation. It is required for energy production, oxidative phosphorylation, and glycolysis.

At the skeletal level, Magnesium is involved in bone formation and influences the activities of osteoblasts and osteoclasts. It also affects the concentrations of both parathyroid hormone and the active form of vitamin D, which are major regulators of bone homeostasis. Research suggests that people with higher levels of Magnesium may have higher bone mineral density, which is important in helping support the risk reduction of bone fractures associated with osteoporosis.

In the nervous system, Magnesium modulates neuronal excitability through voltage-gated Calcium antagonism and N-methyl-D-aspartate (NMDA) receptor blockade. This makes it fundamental for normal nerve signaling and neuromuscular transmission.

For muscles, Magnesium deficiency impairs muscle relaxation β€” muscles contract normally but struggle to fully release when levels are low. A 2024 systematic review found Magnesium supplementation may reduce muscle soreness, improve performance and recovery, and exert a protective effect on muscle damage in physically active individuals.

What's inside

Key Ingredients

Magnesium β€” 250 mg
Magnesium is the fourth most abundant cation in the human body and a cofactor in more than 300 enzyme systems. It supports bone density β€” observational data from large cohort studies found higher Magnesium intake associated with 2–3% greater bone density in women, and clinical trials including the COMB study suggest supplementation may attenuate bone loss. For the nervous system, Magnesium acts as a natural NMDA receptor antagonist, modulating synaptic transmission and neuronal excitability; deficiency is associated with increased risk of neurological symptoms. Research suggests Magnesium may support muscle relaxation and recovery β€” a 2024 systematic review in the Journal of Translational Medicine found supplementation reduced muscle soreness and improved exercise recovery in physically active individuals. It also plays a role in electrolyte balance as a primary intracellular electrolyte required for sodium-potassium ATPase function. EFSA has recognized sufficient evidence that dietary Magnesium contributes to the maintenance of bones and teeth.
Calcium β€” 40 mg
Calcium is the most abundant mineral in the human body, with more than 99% stored in bone as hydroxyapatite. Research suggests Calcium supports bone density β€” meta-analyses of randomized controlled trials demonstrate that supplementation significantly improves bone mineral density, particularly in people under 35 building peak bone mass. Calcium is essential for muscle contraction and relaxation; low intake is associated with muscle spasms, cramps, and weakness, and correction of hypocalcemia resolves neuromuscular symptoms including cramping. In the nervous system, Calcium ions stabilize membrane potential and control the excitability of neurons. As one of the seven primary electrolytes, Calcium supports muscle contraction, nerve transmission, enzyme activity, and blood coagulation. Vitamin D and Magnesium help the body better absorb Calcium.
Phosphorus β€” 30 mg
Phosphorus is the second most abundant mineral in the human body, with approximately 85% residing in bones and teeth as hydroxyapatite, working alongside Calcium to provide structural integrity and strength. It is a component of DNA, RNA, and adenosine triphosphate (ATP), the body's primary energy molecule. For nervous system health, phospholipids β€” which contain Phosphorus as an essential structural element β€” are the primary components of neuronal cell membranes and are required for synaptic neurotransmission. Phosphate-based high-energy molecules fuel all nervous system function. It also helps regulate the normal function of nerves and muscles, including the heart, keeps blood pH within a normal range, and helps the body use carbohydrates and fats for the growth, maintenance, and repair of cells and tissues.
Kelp leaf and stem
Kelp is a form of brown algae rich in vitamins and minerals, and it is an excellent source of dietary iodine. Iodine is an essential trace element required for the biosynthesis of thyroid hormones that regulate energy production, growth, and cellular repair. The Japanese and Chinese cultures used Kelp to treat glandular problems as long ago as 300 BC. Kelp also contains bioactive polysaccharides including alginic acid and laminarin, which have traditionally been valued for their nutritional profile. In traditional medicine systems, Kelp has a long history of use, primarily for the support of glandular function and as a source of essential minerals.
Licorice root
Licorice root (Glycyrrhiza glabra) has been used worldwide as a medicine for over 4,000 years. In traditional Chinese medicine, licorice appears in approximately 60% of prescriptions. It has traditionally been used in herbal medicine to support gastrointestinal comfort, respiratory health including cough and sore throat, and general well-being. The German Commission E approves the use of licorice for catarrhal conditions of the upper respiratory tract. Key constituents include glycyrrhizin, a triterpenoid saponin, along with flavonoids and polyphenols that contribute to its traditional profile.
Peppermint leaves
Peppermint (Mentha Γ— piperita) has been used as a remedy for indigestion since ancient Egyptian times, with dried Peppermint leaves found in pyramids dating back to 1000 B.C. The main constituents are menthol and menthone. Peppermint oil contains L-menthol, which blocks Calcium channels in smooth muscle, producing antispasmodic effects on the gastrointestinal tract. The German Commission E has approved Peppermint leaf for spastic complaints of the gastrointestinal tract. The ancient Greeks and Romans valued it as a stomach soother, and it continues to be used traditionally for digestive comfort.
White willow bark
White willow bark (Salix alba) has been used as a painkiller and antipyretic for more than 3,500 years, dating back to the Sumerians and Egyptians. It contains salicin, a prodrug that is metabolized to salicylic acid and served as the historical precursor to aspirin. White willow bark is traditionally used for muscle pain across European, Native American, and Chinese herbal traditions. Authoritative sources list myalgia as a condition for which willow bark is traditionally used, and Commission E approves it for fever and pain conditions. Its mechanism involves COX-inhibitory and prostaglandin-suppressing activity applicable to muscle inflammation and soreness.
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Who Benefits

Who May Benefit from Magnesium Hydroxide

This formula may be a good fit for adults looking to support their nervous system, maintain healthy bone density, or promote healthy muscle function. Since Magnesium is necessary for the function of over 300 enzymes, its benefits reach across multiple body systems β€” from energy production to proper elimination.

Certain groups are more likely than others to have Magnesium inadequacy, including older adults (due to decreased absorption), individuals with gastrointestinal disorders, those with type 2 diabetes, people with alcohol dependence, and individuals on certain long-term medications such as diuretics or proton pump inhibitors.

It is estimated that between 56 and 68% of Americans do not obtain enough Magnesium in their diet to meet the recommended daily allowance. Early signs and symptoms of deficiency include loss of appetite, nausea, fatigue, and weakness. As deficiency worsens, numbness, tingling, muscle cramps, and abnormal heart rhythms can occur.

If you're unsure whether a Magnesium supplement is right for you, our naturopath is available for a free consultation to help you find the best approach for your individual needs.

Suggested Use

How to Take Magnesium Hydroxide

Take 1 tablet daily with a meal.

Each bottle contains 180 tablets. Calcium and Magnesium are nutritional partners and work best when taken together β€” this formula conveniently includes both minerals. Vitamin D also helps the body better absorb Calcium, so ensuring adequate vitamin D intake alongside this supplement may further support its benefits.

About the author

Written by Greg Howlett

GH

Greg Howlett

Founder

Greg has spent over a decade helping customers choose the right natural-health products. He personally vets every formula we carry and writes these guides to cut through the marketing noise with practical, experience-based advice.

FAQ

Frequently asked questions

What does Magnesium hydroxide do in the body?

Magnesium is a cofactor in more than 300 enzyme systems that regulate diverse biochemical reactions, including protein synthesis, muscle and nerve function, blood glucose control, and blood pressure regulation. It is required for energy production, is involved in bone formation, and modulates neuronal excitability. Nature's Sunshine Magnesium is designed to support nervous system health, bone density, and muscle relaxation.

Why are Calcium and Magnesium included together?

Calcium and Magnesium are nutritional partners and work best when taken together. Magnesium affects the concentrations of both parathyroid hormone and the active form of vitamin D, which are major regulators of bone homeostasis and Calcium metabolism. This formula provides both minerals in a single tablet for convenient daily support.

How common is Magnesium deficiency?

It is estimated that between 56 and 68% of Americans do not obtain enough Magnesium in their diet to meet the recommended daily allowance. Older adults, people with gastrointestinal disorders, those with type 2 diabetes, and individuals taking certain long-term medications like diuretics or proton pump inhibitors are at greater risk of inadequacy.

Can Magnesium help with muscle cramps?

Magnesium is the most studied mineral supplement for skeletal muscle cramps. Magnesium deficiency impairs muscle relaxation β€” muscles contract normally but struggle to fully release when levels are low. A 2024 systematic review found supplementation may reduce muscle soreness and support exercise recovery in physically active individuals, though evidence varies for different types of cramps.

What forms of Magnesium are in this supplement?

Nature's Sunshine Magnesium contains Magnesium oxide and Magnesium amino acid chelate. Magnesium oxide is the most concentrated form by weight. The formula also includes a base of Licorice root, Kelp plant, Peppermint leaves, and White willow bark.

Are there any interactions I should be aware of with Magnesium?

Several medications may interact with Magnesium, including bisphosphonates, tetracycline and quinolone antibiotics, certain diuretics, and proton pump inhibitors (PPIs). Magnesium can form insoluble complexes with some antibiotics, so doses should be separated by at least 2 hours. If you take prescription medications, our naturopath offers free consultations to help you navigate supplement timing and compatibility.

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Magnesium Hydroxide Guide | Caring Sunshine