Chlorogenic acid
Other names for chlorogenic acid
(1s3r,4r,5r)-3-[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-1,4,5-trihydroxycylohexanecarboxylic acid
45% chlorogenic acid
45% total chlorogenic acids
50% chlorogenic acid
50% total chlorogenic acids
cga
chloragenic acids
chlorgenic acids
chlorogenic {acid}
chlorogenic acid
chlorogenic acid derivatives
chlorogenic acid extract
chlorogenic acids
cholorgenci acid
high-cga
min. 2 mg chlorogenic acids
supplying 45% chlorogenic acids
supplying 45% chlorogenic acids and 10% 5-caffeoylquinic acid
supplying chlorogenic acids
total chlorogenic acid
total chlorogenic acids
Synopsis of chlorogenic acid
History
Chlorogenic acid is a naturally occurring polyphenol found in a variety of plants, with especially high concentrations in coffee beans, artichokes, and certain fruits such as apples and pears. Historically, its medicinal use can be traced back centuries, particularly in traditional herbal remedies where plant materials rich in chlorogenic acid were valued for their health-promoting properties. In ancient herbal medicine, decoctions and infusions made from coffee leaves, artichoke, and other botanicals were commonly utilized to support digestion, reduce inflammation, and promote overall vitality.
Remedies containing chlorogenic acid were often prepared as tonics or teas to aid in the management of blood sugar, support healthy metabolism, and contribute to cardiovascular well-being. Its antioxidant and anti-inflammatory properties made it a popular ingredient in folk medicine for alleviating symptoms associated with chronic fatigue, headaches, and minor infections. Additionally, chlorogenic acid-rich plants were sometimes applied topically or consumed to support healthy skin and wound healing.
In herbal combinations, chlorogenic acid frequently acts synergistically with other bioactive compounds. It is often included in blends with green tea, yerba mate, and dandelion to enhance their antioxidant potential and metabolic benefits. Modern nutritional products continue to harness this synergy, formulating supplements that combine chlorogenic acid with various botanicals to maximize wellness outcomes. Overall, chlorogenic acid’s historical and ongoing contributions to herbal medicine highlight its valuable role in promoting health and well-being in a natural, holistic manner.
Traditional and scientific validation
Chlorogenic acid is a naturally occurring polyphenolic compound found abundantly in coffee beans, certain fruits, and vegetables. Historically, foods rich in chlorogenic acid, such as coffee and artichokes, were used in traditional medicine for their perceived health benefits, including supporting metabolism and promoting well-being. In recent years, scientific interest in chlorogenic acid has grown, particularly regarding its potential antioxidant, anti-inflammatory, and metabolic effects.
Several clinical studies have explored the potential of chlorogenic acid in supporting weight management and metabolic health. Some randomized controlled trials have suggested that chlorogenic acid supplementation may help reduce body weight, lower blood pressure, and improve glucose metabolism in certain populations. For example, research published in the journal Diabetes, Metabolic Syndrome and Obesity found that participants consuming green coffee bean extract (a rich source of chlorogenic acid) experienced modest weight loss compared to placebo. Other studies have indicated possible benefits for blood sugar regulation, which could be valuable for individuals with insulin resistance or prediabetes.
Despite these promising findings, the overall evidence base remains limited, and more large-scale, well-designed clinical trials are needed to confirm the efficacy and safety of chlorogenic acid for various health outcomes. Nonetheless, chlorogenic acid’s strong antioxidant properties and its presence in widely consumed foods like coffee have contributed positively to its reputation as a functional ingredient in nutritional products. As research continues, chlorogenic acid holds promise for supporting healthy lifestyles and metabolic function.
Chlorogenic acid is used for these health conditions
Cancer (natural therapy for) (Scientific)
Cancer (prevention) (Scientific)
Cholesterol (high) (Scientific)
Diabetes (Scientific)
Fatty Liver Disease (Scientific)
Hypertension (Scientific)
Inflammation (Scientific)
Metabolic Syndrome (Scientific)
Triglycerides (high) (Scientific)
Weight Loss (Scientific)
chlorogenic acid is used to support these body systems
Arteries (Scientific)
Circulatory System (Scientific)
Heart (Scientific)
Hepatic System (Scientific)
Liver (Scientific)
