Yourzooki Liposomal Vitamin C Zooki Box of 30

Name: Vitamin C (1000 mg, Time Release)
Brand: Nature's Sunshine
SKU: 3240
Price: 35.70 USD
Availability: InStock
Rating: 4.8 (5 reviews)

Discover Nature's Sunshine Vitamin C 1000 mg Time Release with Rose hips, acerola, Rutin & bioflavonoids. Supports immunity, collagen & antioxidant defense.

What It Is

yourzooki liposomal Vitamin C zooki box of 30: A Time-Release Approach to Daily Vitamin C

If you're searching for a reliable, high-potency Vitamin C supplement, Nature's Sunshine Vitamin C (1000 mg, Time Release) is a thoughtfully formulated option worth knowing about. Each tablet delivers 1000 mg of Vitamin C (as ascorbic acid) blended with a synergistic base of Rose hips extract, acerola fruit extract, Rutin, Lemon bioflavonoid extract, and Hesperidin complex — a combination designed to support immune health, antioxidant defense, and collagen production.

What makes this formula stand out is its time-release coating. Rather than releasing all of its Vitamin C at once — where absorption can drop sharply at higher doses — each tablet includes a special coating that slows nutrient absorption until it reaches the intestines. Research confirms that at low gastrointestinal concentrations, active transport predominates, while absorption falls to about 50% or less with doses above 1 g/day. The time-release approach works with your body's natural absorption pathways to help deliver Vitamin C benefits throughout the day.

This is a completely natural product with no sugar, starch, artificial colorings, or flavorings. It's also vegan and non-GMO, arriving in a bottle of 120 tablets (Stock Number 1635-5).

Why It Matters

Why Vitamin C Deserves a Place in Your Daily Routine

Your body cannot make Vitamin C on its own — a quirk of human genetics involving a mutation in the L-gulonolactone oxidase (GLO) gene. That means every milligram must come from food or supplementation. And Vitamin C isn't just a single-purpose nutrient; it's a cofactor for many enzymes involved in collagen biosynthesis, carnitine and catecholamine metabolism, dietary iron absorption, and immune cell function.

Research suggests that Vitamin C contributes to immune defense by supporting various cellular functions of both the innate and adaptive immune system. It helps maintain epithelial barriers against pathogens, enhances the differentiation and proliferation of B cells and T cells, supports phagocytosis, and normalizes cytokine production. Plasma concentrations of Vitamin C decline rapidly during viral infections, underscoring how quickly the body uses this nutrient when it's needed most.

Beyond immunity, Vitamin C is a potent water-soluble antioxidant. Studies suggest it directly scavenges reactive oxygen species in aqueous cellular compartments and can regenerate other antioxidants such as vitamin E. It also plays an essential role in proper folding and deposition of collagen proteins — the most abundant proteins in the human body — supporting skin integrity, wound repair, and connective tissue health.

If you're unsure whether a Vitamin C supplement is right for your needs, our naturopath is available for a free consultation to help you think through the best approach for your individual situation.

What's inside

Key ingredients

Vitamin C (ascorbic acid) — 1000 mg

Vitamin C is a water-soluble essential nutrient that the body cannot synthesize on its own. As an antioxidant, research suggests it directly scavenges reactive oxygen species in aqueous cellular compartments and plasma, and regenerates the antioxidant form of vitamin E at membrane interfaces. Multiple human trials demonstrate that supplementation raises antioxidant capacity and reduces biomarkers of oxidative damage. For immune support, studies suggest Vitamin C accumulates in leukocytes, supports phagocytosis and chemotaxis, and is rapidly consumed during infection. A Cochrane review of 29 trials involving over 11,000 participants found that regular supplementation modestly reduces common cold duration (8% in adults, 14% in children) and severity, with greater preventive benefit observed in populations under heavy physical stress. Vitamin C also plays an essential role in collagen biosynthesis — without adequate levels, prolyl and lysyl hydroxylase enzymes cannot properly hydroxylate collagen precursors, which is critical for skin, connective tissue, and wound repair. Additionally, it enhances absorption of non-heme iron by reducing ferric iron (Fe³⁺) to ferrous iron (Fe²⁺) in the gastrointestinal lumen.

Rose hips — 25 mg

Rose hips (Rosa canina) are among the richest natural plant sources of Vitamin C, with concentrations that can reach up to 1,300 mg per 100 g depending on source and processing. They also provide polyphenols, carotenoids (including lycopene and beta-carotene), tocopherols, and flavonoids, giving them exceptionally high antioxidant capacity — rose hip extract ranks among the highest measured antioxidant activities of tested fruits by ORAC, TRAP, and HORAC assays. Research suggests that clinical studies confirm increased antioxidant status in healthy adults following supplementation. Traditionally, rose hip tea and syrup have been used for centuries as a cold-season immune staple. Meta-analyses of Vitamin C supplementation — the principal bioactive in Rose hips — show an 8–14% reduction in cold duration in adults, directly supporting upper respiratory health.

acerola fruit extract — 25 mg

Acerola (Cherry) fruit is a concentrated source of anthocyanins — polyphenolic compounds with potent antioxidant activity. Research suggests that tart Cherry anthocyanins upregulate endogenous antioxidant pathways, including Nrf2/ARE, and human randomized controlled trials show increased DNA repair enzyme (OGG1) activity and reduced oxidative stress markers such as MDA and oxidized LDL following supplementation. Studies also suggest that Cherry anthocyanins modulate immune-inflammatory signaling by inhibiting COX-1/2 and NF-κB, reducing TNF-α, IL-1β, and IL-6 in human studies, and that RCTs demonstrate reduced C-reactive protein after exercise and at rest in older adults.

Rutin — 25 mg

Rutin (quercetin-3-O-rutinoside) is a flavonoid glycoside found in buckwheat, citrus fruits, and many plants. Research suggests it is a well-documented antioxidant through multiple mechanisms: direct free-radical scavenging, upregulation of endogenous antioxidant enzymes (SOD, CAT, GPx), and activation of the Nrf2/ARE pathway, with preclinical evidence consistently showing reductions in oxidative stress biomarkers such as MDA and ROS. A human supplementation trial confirmed that six weeks of Rutin supplementation significantly elevated plasma flavonoid levels including quercetin. For immune modulation, studies suggest Rutin suppresses pro-inflammatory cytokine production from macrophages, inhibits mast cell activation relevant to allergic immunity, modulates Th1/Th2 balance, and exerts NF-κB-dependent immunomodulatory effects documented in human and animal studies.

Hesperidin bioflavonoid extract — 25 mg

Hesperidin is a flavanone glycoside predominantly found in citrus fruits, especially oranges and lemons. Research suggests it is a potent natural antioxidant that scavenges reactive oxygen species, enhances endogenous antioxidant enzyme activity (SOD, CAT, GSH), and activates the ERK/Nrf2 signaling pathway — effects demonstrated in vitro, in animal studies, and in human RCTs measuring oxidative stress biomarkers. For immune modulation, studies suggest Hesperidin downregulates pro-inflammatory cytokines (TNF-α, IL-1β, IL-4, IL-6, IL-8, IL-12) and upregulates anti-inflammatory IL-10, inhibits NF-κB, and modulates leukocyte function. A human RCT showed that a Hesperidin-containing supplement improved immune function in adults and enhanced the oxidative-inflammatory state.

Lemon bioflavonoid extract — 25 mg

Lemon bioflavonoids include Hesperidin, eriocitrin, diosmin, and other flavonoid compounds found in citrus peel and pulp. Research suggests that Lemon is a well-characterized source of Vitamin C and flavonoids with documented antioxidant capacity in human studies — a double-blind RCT showed that citrus extract combined with Vitamin C significantly increased lipoprotein oxidation lag time, outperforming vitamin E as an antioxidant. For immune support, Lemon's Vitamin C content supports multiple immune functions including natural killer cell activity, lymphocyte proliferation, neutrophil function, and interferon production. Clinical evidence documents that Vitamin C supplementation reduces severity and duration of respiratory infections.

dicalcium phosphate

Dicalcium phosphate serves as a tablet base and provides a small amount of Calcium, the most abundant mineral in the human body. More than 99% of the body's Calcium is stored in bone as hydroxyapatite, and Calcium plays essential roles in muscle contraction, nerve transmission, and cellular signaling. While the primary purpose of dicalcium phosphate here is as a tableting agent, dietary Calcium is recognized as crucial for bone health and normal physiological function.

Vitamin C (1000 mg, Time Release)

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Vitamin C (1000 mg, Time Release)

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Who It's For

Who May Benefit from This Time-Release Vitamin C

This formula is well-suited for adults looking for comprehensive daily Vitamin C support — particularly those focused on immune health, antioxidant defense, or collagen support for skin and connective tissue. The time-release design may be especially helpful for anyone who wants sustained Vitamin C delivery rather than a single large dose.

People who experience seasonal immune challenges or who want to support their body during cold and flu season may find the combination of Vitamin C with bioflavonoids like Rutin, Hesperidin, and Rose hips particularly appealing. Research suggests that these plant compounds provide complementary antioxidant and immune-modulating support that may work synergistically with ascorbic acid.

Because this product is vegan and non-GMO with no sugar, starch, artificial colorings, or flavorings, it's a clean option for those who are mindful about what goes into their supplements. If you have questions about whether this formula fits your individual needs — especially if you take medications or have a specific health concern — our naturopath offers free consultations and would be happy to help.

How To Take

Directions for Use

Take one tablet daily with a meal. The time-release coating is designed to slow nutrient absorption until the tablet reaches the intestines, helping to deliver Vitamin C benefits throughout the day rather than all at once.

About the author

Written by Greg Howlett

Greg Howlett

Founder

Greg has spent over a decade helping customers choose the right natural-health products. He personally vets every formula we carry and writes these guides to cut through the marketing noise with practical, experience-based advice.

FAQ

Frequently asked questions

What makes this Vitamin C formula different from a standard Vitamin C tablet?

Each tablet includes a special time-release coating that slows absorption of the nutrients until they reach the intestines. Research shows that at high doses, Vitamin C absorption can drop to about 50% or less, so the time-release design helps work with your body's natural absorption pathways. The formula also blends Vitamin C with a base of Rose hips extract, acerola extract, Rutin, Lemon bioflavonoids, and Hesperidin complex for complementary antioxidant support.

How does Vitamin C support the immune system?

Research suggests Vitamin C contributes to immune defense by supporting various cellular functions of both the innate and adaptive immune system. It helps maintain epithelial barrier function against pathogens, enhances the differentiation and proliferation of B cells and T cells, supports phagocytosis, normalizes cytokine production, and decreases histamine levels. Plasma concentrations of Vitamin C decline rapidly during infections, which underscores the body's increased demand for this nutrient during immune challenges.

Is this product suitable for vegans?

Yes, this formula is vegan and non-GMO. It contains no sugar, starch, artificial colorings, or flavorings.

Why are bioflavonoids like Rutin and Hesperidin included alongside Vitamin C?

Rutin, Hesperidin, Rose hips, acerola, and Lemon bioflavonoids each bring their own antioxidant and immune-modulating properties. Research suggests Rutin scavenges free radicals and upregulates endogenous antioxidant enzymes, Hesperidin activates the ERK/Nrf2 signaling pathway, and Rose hips rank among the highest measured antioxidant activities of tested fruits. Together, they complement and extend the benefits of ascorbic acid.

How many tablets are in a bottle, and how long does it last?

Each bottle contains 120 tablets. At the recommended serving of one tablet daily, a single bottle provides a four-month supply.

Can I take this Vitamin C if I'm already taking other supplements or medications?

Vitamin C can interact with certain medications, including chemotherapy drugs, statins combined with niacin, estrogen-containing medications, protease inhibitors, and iron supplements. It also enhances iron absorption, which may be a concern for people with hemochromatosis. If you take any medications or have specific health conditions, we'd recommend speaking with a healthcare professional. Our naturopath is available for a free consultation to help you evaluate the best approach.

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