Nature's Sunshine
Stock #: 1398
Berberine IR
90 CapsulesStock #: 1398
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Availability: In stock as of 05/10/2026
Expiration Date: 08/2027
Free returns for 90 days
Technical information
Ingredient list
| Ingredient | Amount |
| Berberine from Indian barberry | 333 mg |
Other ingredients: cellulose, magnesium stearate, silicon dioxide, vegetable capsule (hypromellose, water)
Recommended Use
Take 1 VegCap before a meal, three times daily.
Serving size: 1
Days Supply: 30
Cost Per Day: $1.50
Product Categories: Blood Sugar, Circulatory System, Herbs (Ayurvedic)
UPC: 099904013988
Product Information
Why take this product?
- Stimulates enzymes that metabolize blood glucose
- Promotes healthy blood glucose levels
- Combats endotoxins
How it works
Flip your switch to “lovin’ life”. Berberine switches cells from “idle” to “on”, so they use glucose more efficiently and take your feel-good to a whole new level.
Glucose Metabolism Support Berberine naturally supports healthy blood glucose levels by up-regulating enzymes that trigger blood glucose metabolism. Utilizing a time-honored ingredient found in both Traditional Chinese and Ayurvedic formulas, Berberine works to support blood sugar balance and glucose metabolism through a unique cellular action. Berberine, a constituent of certain plants, helps activate a key enzyme that supports blood glucose metabolism, turning your cells from “idle” to “on” and helping them to use glucose efficiently. Additionally, Berberine supports healthy gut performance to help combat endotoxins. High-carbohydrate diets change the microflora of the gut, increasing bacteria that produce endotoxins. These endotoxins are released into the bloodstream and interfere with normal glucose metabolism. Berberine specifically supports gut health by inhibiting the ability of endotoxins to bind to muscle cells, thus helping to support proper glucose metabolism function. Its unique mechanism of action makes Berberine an excellent option for those who wish to start or strengthen their glucose management regimen. Support your body’s ability to metabolize blood glucose with Berberine.
WHY OUR BERBERINE?
The Himalayan Mountains provide rich biodiversity, featuring a host of natural plant life. Berberis aristata flourishes in this region and the adjoining hill country. The root’s berberine content and activity has been found to be dependent on the altitude at which the plant grows and its soil content: it thrives in a potassium-rich environment.
Our relationship with our berberine supplier goes back more than 15 years. It includes active involvement with the farming community and wild crafters, and a personal audit of their processing facilities. Our berberine is non-GMO verified, and Kosher- and Halal-certified.
THE STORY BEHIND BERBERINE
Berberine. Berberis aristata is an Indian medicinal plant from the family Berberidaceae. This Ayurvedic shrub was used anciently by many cultures. The Egyptians used barberry fruit for immune support. In India, they used barberry fruit to help balance the fluid levels in the bowel. Russian proponents used barberry for circulatory concerns. And in Iran, they employed it for its ability to settle and soothe the circulatory and nervous systems. Other names for this species include Indian berberi, tree turmeric, jaundice berry, Daruharidra and Darvi. Native to the mountains of India and Nepal, it now grows in temperate climates across Europe, Asia and America.
Frequently Asked Questions
Berberine IR is Nature's Sunshine's glucose metabolism support formula featuring berberine, a plant-based compound used in both Traditional Chinese and Ayurvedic traditions. It's designed to help activate key enzymes that support healthy blood sugar balance and help your cells use glucose more efficiently.
Berberine works by up-regulating enzymes that trigger blood glucose metabolism, essentially switching your cells from 'idle' to 'on' so they can use glucose more efficiently. It also supports healthy gut performance by helping combat endotoxins — harmful byproducts from gut bacteria that can interfere with normal glucose metabolism, especially in those consuming high-carbohydrate diets.
Berberine IR may be a good fit for anyone looking to support healthy blood sugar levels already within a normal range, or those seeking metabolic wellness support. People who consume a higher-carbohydrate diet may also appreciate its gut-supportive properties. As always, we recommend consulting your healthcare provider before starting any new supplement.
Each bottle contains 90 capsules. We recommend following the dosage instructions on the label, and taking it with meals for best results. If you have questions about what serving size is right for you, your healthcare provider can offer personalized guidance.
Berberine IR is unique in the Nature's Sunshine line because it focuses specifically on cellular-level glucose metabolism through the activation of key enzymes, while also addressing gut health and endotoxin balance. Other blood sugar support products in the line may use different herbal approaches, so Berberine IR is a great option if you're specifically looking for the well-researched benefits of berberine from the Ayurvedic tradition.
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